Results 111 to 120 of about 18,724 (299)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Consolidation Process and Triaxial Shear Test of Consolidation Coefficient for Saturated Soft Soil in Marsh

open access: yes, 2011
The consolidation coefficient is the important parameters for soft soil foundation to predict its consolidation settlement. At present, one-way compression test is mainly used to study consolidation process and consolidation coefficient of soft soil. For
Xia Xin Tao   +3 more
core   +1 more source

Laboratory Investigation on Shear Modulus and Damping Properties of Port Soft Clay Improved by Dynamic Compaction

open access: yesApplied Sciences
Dynamic compaction has been widely applied to reinforce soft soils in port areas due to its high efficiency and cost-effectiveness. However, a comprehensive understanding of the deformation mechanisms and stiffness evolution of treated soils under static
Chenyu Hou   +6 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

"Effects of Bank Consolidation Promotion Policy: Evaluating the Bank Law in 1927 Japan" [PDF]

open access: yes
This paper investigates the impact of bank consolidations promoted by government policy, using data from prewar Japan, when the financial authorities promoted them by dint of the Bank Law in 1927.
Michiru Sawada, Tetsuji Okazaki
core  

Appraisal of observational method for consolidation analysis

open access: yes, 2014
Two of the aims of laboratory one-dimensional consolidation tests are prediction of the end of primary settlement, and determination of the coefficient of consolidation of soils required for the time rate of consolidation analysis from time-compression ...
Sridharan, A   +2 more
core   +1 more source

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