Results 71 to 80 of about 30,790,443 (235)
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Observations of a Footpoint Drift of an Erupting Flux Rope
International audienceWe analyze the imaging observations of an M-class eruptive flare of 2015 November 4. The pre-eruptive Hα filament was modeled by the nonlinear force-free field model, which showed that it consisted of two helical systems.
Thalmann, Julia +4 more
core +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
A model of an isolated magnetic-flux tube in a stratified atmosphere
A two-dimensional model of a magnetic flux tube confined in a gravitational stratified atmosphere is discussed. The magnetic field in the flux tube is assumed to be force-free.
HU, WR (reprint author), CHINESE ACAD SCI,INST MECH,BEIJING,PEOPLES R CHINA. +1 more
core +1 more source
Magnetic flux density distribution in axial flux machine cores [PDF]
[Abstract]: A three-dimensional analytical model is presented to evaluate the magnetic flux density distribution in the core of an axial flux machine. The model predicts significantly higher flux density near the outer radius of the core than that at the
Hewitt, Andrew +2 more
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The flow rate of the oil-water horizontal flow is measured by the combination of the turbine flow meter and the single-beam gamma ray densitometry. The emphasis is placed on the effects of the pipe diameter, the oil viscosity and the slip velocity on the
许晶禹 +2 more
core +1 more source
Pattern formation through genetic drift at expanding population fronts [PDF]
We investigate the nature of genetic drift acting at the leading edge of range expansions, building on recent results in [Hallatschek et al., Proc. Natl. Acad. Sci., 104(50): 19926-19930 (2007)].
Adnan Ali +3 more
core +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source

