Results 131 to 140 of about 16,677,913 (308)

TWO-STAGE QUANTILE REGRESSION WHEN THE FIRST STAGE IS BASED ON QUANTILE REGRESSION [PDF]

open access: yes
We present the asymptotic properties of double-stage quantile regression estimators with random regressors, where the first stage is based on quantile regressions with the same quantile as in the second stage, which ensures robustness of the estimation ...
Tae-Hwan Kim, Christophe Muller
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

[Stage Two Landscapes 29]

open access: yes, 2003
Wet on wet landscape with building shapes; black, green and yellow foreground; black and red sky. On same sheet as [Stage Two Landscapes 24]Tiff file: 2120x3330 pixels, 20.2 Mb; Display: jpeg, 530x797 pixels ...
Father Edward Catich
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

[Stage Two Landscapes 27]

open access: yes, 2003
Wet on wet landscape of white, gray, green; blue houses; black foreground and blue sky. On same sheet as [Stage Two Landscapes 21].Tiff file: 2220x3330 pixels, 21.2 Mb; Display: jpeg, 533x800 pixels ...
Father Edward Catich
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

[Stage Two Landscapes 28]

open access: yes, 2003
Wet on wet landscape with building shapes; brown, green, yellow and dark blue foreground; black and blue sky. On same sheet as [Stage Two Landscapes 25]Tiff file: 2290x3310 pixels, 21.7 Mb; Display: jpeg, 572x772 pixels ...
Father Edward Catich
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The impact of the “One Belt One Road” initiative on countries along route

open access: yes, 2019
“One Belt One Road” is a national cooperation initiative initiated by China. It is put forward against the backdrop of deepening economic globalization and accelerating regional economic integration.
Li, Huanhuan
core  

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