Results 61 to 70 of about 1,468,636 (262)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

One-way Video Transmission Technology for Urban Rail Transit Based on EndpointDevices

open access: yesChengshi guidao jiaotong yanjiu
[Objective] To meet the integrity, confidentiality and availability requirements for inter-network video transmission of different security levels in urban rail transit system, it is necessary to develop a secure and reliable one-way video transmission ...
ZHANG Lidong, XU Ziheng, WANG Kun
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Private Key and Group Key Generation Using Correlated Sources and Wiretap Broadcast Channel in Presence of One-Way Public Communication

open access: yesIEEE Access, 2019
Encryption with shared key is one of the methods to ensure secure communication. To meet the requirements of keys, this paper investigates the problem of generating private key (PK) and group key (GK) using correlated sources and discrete memoryless ...
Shixun Gong   +3 more
doaj   +1 more source

Exploring the intersections: Researchers and communication professionals' perspectives on the organizational role of science communication [PDF]

open access: yes, 2020
Purpose: This paper reports on research exploring the intersections between researchers and communication professionals' perspectives on the objectives, funders and organizational influences on their science communication practices.
Wilkinson, Clare   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Ouverture de ‘Communication and Global Markets’

open access: yesSymphonya, 2006
Communication is a complex phenomenon, with numerous scientific and operational dimensions, the most significant of which are: psychology, sociology, technology, legal, ethics, economics and management.
Silvio M. Brondoni
doaj   +1 more source

Redefinition of Feedback in Corporate Communication Management and Target Group Relations: A Literature Review

open access: yes, 2019
Limitations of time and place during the communication process have been removed with the advent of new communication technologies, and the target groups that used to have a passive role as the receiver of a message in communication conducted with the ...

core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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