Results 71 to 80 of about 1,468,636 (262)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Outage probability analysis of vehicular communication system with two-way AF cooperation

open access: yesDianzi Jishu Yingyong, 2018
In vehicular communication system, two-way cooperative communication can improve system performance. However, vehicle mobile communication will cause the two-way link correlation and thus reduce the system outage performance.
Lin Xiaoyu, Qiu Bin, Xiao Hailin
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

THE ROLE OF INTERNAL COMMUNICATION ON THE EFFICIENCY OF THE ACTIVITY IN AN ORGANIZATION [PDF]

open access: yesBusiness Excellence and Management, 2017
The present paper, entitled "The role of internal communication on the efficiency of the activity in an organization", aims to identify the importance of internal communication in any organization and especially to identify the way in which the strategy ...
Florentina PÎRJOL , Lia Lucica RADOMIR
doaj  

The convergence model of communication [PDF]

open access: yes, 1979
For more about the East-West Center, see http://www.eastwestcenter.org/This paper develops a general model of the communication process based upon the principle of convergence as derived from basic information theory and cybernetics.
Kincaid, D. Lawrence
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The One-Way Communication Complexity of Dynamic Time Warping Distance [PDF]

open access: yes, 2019
We resolve the randomized one-way communication complexity of Dynamic Time Warping (DTW) distance. We show that there is an efficient one-way communication protocol using O~(n/alpha) bits for the problem of computing an alpha-approximation for DTW ...
Woodruff, David P   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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