Results 31 to 40 of about 189,557 (298)

Evaluation on Flexural Performance of One-Way Hollow Slabs according to the Shear Reinforcement [PDF]

Journal of the Korean Association for Spatial Structures, 2014
The purpose of this study is intended to determine the validity of shear reinforcement by evaluating flexural performance in the hollow slab. The hollow slab is relatively light and second moment of inertia is large. Due to these characteristics, it can be used to slab system efficiently.
Yu-Jin Yu, Keun-Young Seok, Gee-Cheol Kim, Joo-Won Kang   +3 more
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Linear instability of planar shear banded flow of both diffusive and non-diffusive Johnson-Segalman fluids

, 2006
We consider the linear stability of shear banded planar Couette flow of the Johnson-Segalman fluid, with and without the addition of stress diffusion to regularise the equations.
Wilson, HJ, Wilson, Helen J., Fielding, SM, Wilson, H.J., Fielding, Suzanne M., Fielding, S.M.   +5 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Consideration on punching shear strength of steel-fiber-reinforced concrete slabs

Advances in Mechanical Engineering, 2015
The flat plate slab system is widely used in construction fields due to its excellent constructability and savings in story height compared to the conventional beam-column moment-resisting system.
Hyunjin Ju, Na-Rae Cheon, Deuck Hang Lee, Jae-Yuel Oh, Jin-Ha Hwang, Kang Su Kim   +5 more
doaj   +1 more source

ONE-WAY SLABS IN TRANSITION BETWEEN ONE-WAY SHEAR AND PUNCHING: EXPERIMENTS AND RECENT INSIGHTS FOR EVALUATION

Proceedings of International Structural Engineering and Construction
Bridge deck slabs are members on which one-way reinforced concrete slabs are found frequently loaded by concentrated loads. Although the one-way shear failure mechanism has gathered more attention in the past years, both one-way shear and two-way shear mechanisms may be critical for such loading conditions. This paper addressed the ultimate capacity of
Alex Micael Dantas de Sousa, Eva Olivia Leontien Lantsoght, Mounir Khalil El Debs   +2 more
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Shear instabilities in shallow-water magnetohydrodynamics [PDF]

, 2013
The interaction of horizontal shear flows and magnetic fields in stably stratified layers is central to many problems in astrophysical fluid dynamics.
Mak, Julian
core