Results 31 to 40 of about 21,052,493 (282)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
MathematicsThis article shows a model for the design of circular isolated footings and the column placed anywhere in the footing under minimum cost criteria. Some designs for obtaining the diameter, effective depth, and steel areas of the footing under biaxial ...
Arnulfo Luévanos-Rojas +6 more
doaj +1 more source
Alexandria Engineering Journal, 2015 An experimental and analytical study on the punching strengthening of reinforced concrete two-way slabs using external steel plates is presented. Five reinforced concrete square slabs of 100 mm thickness were tested over simply supported four sides of ...
Hazem M.F. Elbakry, Said M. Allam
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Evaluation on Flexural Performance of One-Way Hollow Slabs according to the Shear Reinforcement [PDF]
Journal of the Korean Association for Spatial Structures, 2014 The purpose of this study is intended to determine the validity of shear reinforcement by evaluating flexural performance in the hollow slab. The hollow slab is relatively light and second moment of inertia is large. Due to these characteristics, it can be used to slab system efficiently.
Yu-Jin Yu +3 more
openaire +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Case Studies in Construction Materials, 2022 Despite 70 years of investigations in understanding the shear behaviour of reinforced concrete members, it is again gaining attention among structural engineers as the recently issued Australian concrete design standard, AS 3600 updated its shear ...
Thushara Jayasinghe +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Consideration on punching shear strength of steel-fiber-reinforced concrete slabs
Advances in Mechanical Engineering, 2015 The flat plate slab system is widely used in construction fields due to its excellent constructability and savings in story height compared to the conventional beam-column moment-resisting system.
Hyunjin Ju +5 more
doaj +1 more source