Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Branch Input Resistance and Steady Attenuation for Input to One Branch of a Dendritic Neuron Model (1973) [PDF]
Wilfrid Rall, John Rinzel
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The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
This item contains two issues of the Take One newsletter: November 8, and 22, 1984Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
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Sr$_3$LiIrO$_6$: a potential quantum spin liquid candidate in the one dimensional $d^4$ iridate family [PDF]
A. Bandyopadhyay +10 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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Commentary: how long does one need to fast before a Fibroscan examination? [PDF]
Kelvin Long‐Yan Lam +2 more
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Undergraduate Pharmacology Written Question Papers of Different Universities of Bangladesh: Analysis of One Decade [PDF]
Fatema Johora +5 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Contracts and Competition in the Pay-TV Market [PDF]
Contracts, licensing, pay ...
Author One David Harbord +1 more
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