Results 191 to 200 of about 42,469,765 (329)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

One-to-One Program: Day 32 [PDF]

, 2017
Crooks, Roderic
core   +1 more source

Retraction: An improved DBSCAN algorithm based on cell-like P systems with promoters and inhibitors. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Our Hope: One Lord, One Faith, One Baptism [PDF]

, 1969
Mullooly, John P.
core   +1 more source

Expression of Concern: Ensemble learning approach for advanced metering infrastructure in future smart grids. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Polycylic N-Heterocyclic Compounds. 53. One Step Synthesis of Imidazo[1,5-a]pyridine Derivatives by Vilsmeier Reaction Using N,N-Dimethylarylamides

, 1999
Takashi Hirota, Kenji Sasaki, Akifumi Tsurumori, Setsuo Kashino   +3 more
openalex   +1 more source

Replication Data for One Person, One District: Democratically Driven Redistricting Standards

, 2023
Geoffrey Wise
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Expression of concern: Optimizing load scheduling and data distribution in heterogeneous cloud environments using fuzzy-logic based two-level framework. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source