Results 61 to 70 of about 29,312,700 (253)

Comparison between immunohistochemical expression of Ki-67 and MCM-3 in major salivary gland epithelial tumors in children and adolescents. Preliminary study

open access: yesPolish Journal of Pathology, 2017
While Ki-67 expression is frequently used as an indicator of tumor cell proliferation, alternative markers have also been proposed. Possible alternative indicators of proliferation are the minichromosome maintenance (MCM) proteins, whose levels are ...
Rafał Zieliński   +2 more
doaj   +1 more source

Comparison of the World Pharmacopoeias’ Requirements for the Quality of Cell Lines

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2020
The cell line is one of the necessary components of a biomedical cell product (BMCP) which can include only viable human cells. In addition, human, animal, insect, or bacterial cell lines can be used as a substrate for the production of some biological ...
M. A. Vodyakova   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]

open access: yes, 2011
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Haastert, Peter J.M. van,   +26 more
core   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Cortisol level decreases natural killer cell activity among women exposed to aircraft noise [PDF]

open access: yesUniversa Medicina, 2010
One of the impacts of exposure to noise is stress. Natural killer (NK) cells are one of the leukocyte subsets that are responsive to physiological and psychological stress.
Hartono
doaj  

Family Sculpture with Playmobil Pieces

open access: yes
Mit dem FSPlay werden innere "Arbeitsmodelle" (Schemata) von Bindungs-/Familien-/Partnerschafts-/Freundschaftsbeziehungen erhoben. Anhand mehrerer Spielfiguren sollen eine oder mehrere Skulpturen gestaltet werden, z. B.
Sydow, K. v.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Complete Meniscus Removal Method for Broadband Liquid Characterization in a Semi-Open Coaxial Test Cell

open access: yesSensors, 2019
We present a new technique for broadband liquid characterization using a semi-open, vertically oriented test cell that is measured with a calibrated vector network analyzer in three states: the empty one and filled with two different volumes of the ...
Michał Kalisiak, Wojciech Wiatr
doaj   +1 more source

PCS-Q-G. Parental Caregiving Style Questionnaire – German Version

open access: yes
Der PCS-Q-G dient der retrospektiven Erfassung des elterlichen Fürsorgeverhaltens. In Analogie zum 3-Kategorien-Modell von Bindung unterscheidet das Instrument zwischen den drei Stilen „warm/aufmerksam“, „ambivalent/inkonsistent“ und „kalt/abweisend ...
Rohmann, E., Neumann, E.
core   +1 more source

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