Results 201 to 210 of about 35,039,938 (235)

Correction: Health system costs and systemic treatment patterns by disease stage for 8577 people diagnosed with melanoma in New South Wales, Australia 2006-2019. [PDF]

PLoS One
Goldsbury DE, Cust AE, Watts C, Pearce A, Haywood P, Collins LG, Ngo P, McLoughlin K, Caruana M, Canfell K, Steinberg J, Weber MF.   +11 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Contested cultures of care: research with and for the plus one community on the plus one experience - evaluation report [PDF]

, 2019
Benaton, Tonimarie, Nunn, Alex, Bowers-Brown, Tamsin, Dodsley, Thomas, Manning-Jones, Alix, The Plus One Community, Murden, Jade   +6 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Ancient DNA study resolves the taxonomic status of the extinct large Palaearctic crane <i>Grus primigenia</i> Milne-Edwards, 1871 (Aves: Gruiformes: Gruidae). [PDF]

R Soc Open Sci
Stewart JR, Rickard R, Hamilton-Dyer S, Dobney K, Laroulandie V, Alcover JA, Femenias-Gual J, Pöllath N, Ersmark E, Cronholm B, Ericson PGP, Dalén L.   +11 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

PDKE-G: A Bio-Inspired Contributory Group Authenticated Key Exchange Grounded in Per-Member AlphaFold2 Protein Geometry. [PDF]

Biomimetics (Basel)
Alabdulatif A.
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Mate choice copying in non-human animals: an update of two meta-analyses. [PDF]

Biol Open
Santos ESA, Milenović A, Arct A, Lenz A, Mizuno A, Schneider C, Sosiak C, Lundgren E, Qin H, Gross I, Celeste J, Morrison K, Zakir M, Purgar M, Ortega S, Hernandez S, Nakagawa S, Lagisz M.   +17 more
europepmc   +1 more source