Results 91 to 100 of about 278,401 (296)

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F, Koenigsknecht, Carmon, Lakshminrusimha, Satyan, Mathew, Bobby, Nair, Jayasree, Nielsen, Lori, Rawat, Munmun, Swartz, Daniel D   +7 more
core  

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Cerebral Desaturation and One-Lung Ventilation [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2021
Bryan E. Marchant, Scott A. Miller, Roger L. Royster   +2 more
openaire   +2 more sources

Anaesthesia for serial whole-lung lavage in a patient with severe pulmonary alveolar proteinosis: a case report [PDF]

, 2008
Introduction Pulmonary alveolar proteinosis is a rare condition that requires treatment by whole-lung lavage. We report a case of severe pulmonary alveolar proteinosis and discuss a safe and effective strategy for the anaesthetic management of patients ...
Stephen T Webb, Adrian JR Evans, A James Varley, Andrew A Klein, BC Trapnell, J Ramirez-Rivera, R Bingisser, R Ahmed, M Moutafis, M Nadeau, R Ben-Abraham   +10 more
core   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

An investigation into the effects of commencing haemodialysis in the critically ill [PDF]

, 2012
<b>Introduction:</b> We have aimed to describe haemodynamic changes when haemodialysis is instituted in the critically ill. 3 hypotheses are tested: 1)The initial session is associated with cardiovascular instability, 2)The initial ...
Docking, R., Kinsella, J., Moss, L., Sim, M., Sleeman, D.   +4 more
core   +2 more sources

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Distribution of Capillary Transit Times in Isolated Lungs of Oxygen-Tolerant Rats [PDF]

, 2010
Rats pre-exposed to 85% O2 for 5–7 days tolerate the otherwise lethal effects of 100% O2. The objective was to evaluate the effect of rat exposure to 85% O2 for 7 days on lung capillary mean transit time (t¯c) and distribution of capillary transit times (
AB Fisher, AB Fisher, AJ Schwab, Anne V. Clough, AV Clough, BA Freeman, BA Freeman, CA Dawson, CA Goresky, D Jamieson, David L. Roerig, DJ Kwak, E Cadenas, G Capellier, G Lenaz, JB Bassingthwaighte, JD Crapo, JD Crapo, JD Crapo, JE Heffner, JF Turrens, JM Gonzalez-Fernandez, K Howell, K Sjostrom, KH Albrecht, L Frank, Madhavi Ramakrishna, ML Zierhut, MP Merker, MP Merker, NC Staub, OD Saugstad, R Beasley, RD Bongard, RD Bongard, RE Kimball, RG Presson Jr, RG Presson Jr, Robert C. Molthen, RR Mercer, S Valenca Sdos, Said H. Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Audi, SH Randell, V Bhandari, V Kim, W Shi, WG Guntheroth, WS Miller, YS Ho, Zhuohui Gan   +59 more
core   +2 more sources

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Healthcare professional’s guide to cardiopulmonary exercise testing [PDF]

, 2015
Cardiopulmonary exercise testing (CPEX) is a valuable clinical tool that has proven indications within the fields of cardiovascular, respiratory and pre-operative medical care.
Frenneaux, Michael P., Gollop, Nicholas D., Loudon, Brodie L., Parasuraman, Sathish, Schwarz, Konstantin   +4 more
core   +1 more source