Results 191 to 200 of about 14,534,614 (293)

Hypoxia synergizes cGAS-STING activation and AKT1 phosphorylation to drive pulmonary inflammation in one-lung ventilation: therapeutic attenuation by RU.521 and MK2206. [PDF]

J Inflamm (Lond)
Zhang J, Zou Y, Chen D, Fan J, Men B, Cai Y, Yuan X, Ye T, Cai K.   +8 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Adapted Linear Binning Method to Assess Pulmonary Ventilation and Perfusion in Children Using Lung Matrix Pencil Decomposition (MP)‐MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To adapt and validate a linear binning technique, developed for hyper‐polarized 129Xe MRI, for functional lung MRI with matrix‐pencil decomposition (MP)‐MRI. Methods First, a dedicated normalization was applied to the perfusion‐weighted and the ventilation‐weighted map histograms.
Marion Curdy, Carmen Streibel, Oliver Bieri, Elisabeth Kieninger, Florian Wyler, Lukas Ebner, Grzegorz Bauman, Philipp Latzin   +7 more
wiley   +1 more source

Mechanical power during one-lung ventilation is associated with postoperative pulmonary complications in patients undergoing lobectomy: a single-center prospective cohort study. [PDF]

BMC Anesthesiol
Zhang Y, Wang X, Zhang Z, Zhang Y, Deng Z, Lei X, Liu L, Bai Y, Scharffenberg M, Wang X.   +9 more
europepmc   +1 more source

Image‐Derived Volumetry During Forced Expiration Using a 3D Fermat Looped, Orthogonally Encoded Trajectory

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To enable MRI‐based nongated 3D depiction of forced expiration with both high spatio‐temporal resolution and fidelity of lung dynamics. Methods An undersampled 3D Fermat looped, orthogonally encoded trajectory (FLORET) was optimized for nonsegmented dynamic acquisitions during forced expiration and a corresponding model‐based ...
Sebastian Scheidel, Viktor Hartung, Matthias Stephan Anders, Corona Metz, Herbert Köstler, Simon Veldhoen, Tobias Wech   +6 more
wiley   +1 more source

Effect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial. [PDF]

Thorax
Glass A, O'Kane CM, Dhrampal A, Fontaine E, Ryan J, Loubani M, Rathinam S, Naidu B, Welters ID, Silversides J, Alkhaffar B, Hayden J, Griffiths E, Chan D, Doran A, Toase S, Campbell C, Agus A, Perkins GD, McAuley DF, Shyamsundar M.   +20 more
europepmc   +1 more source

Correlating Pulmonary Hemodynamics With HP 129Xe Dissolved‐Phase MRSI in a Controlled Porcine Intervention Study

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Pulmonary hypertension is related to a 1‐year mortality ranging from < 5% to > 20% in low‐ and high‐risk groups. Right heart catheterization is the diagnostic gold standard, associated with a 1.1% rate of severe adverse events, posing the need for a non‐invasive diagnostic tool.
Markus Phillip Andersen, Mattias Hedegaard Kristensen, Esben Søvsø Szocska Hansen, Rolf F. Schulte, Mohsen Redda, Uffe Kjærgaard, Michael Vaeggemose, Christoffer Laustsen   +7 more
wiley   +1 more source

Evaluating the Impact of Clonidine and Midazolam Premedication on Emergence Delirium in Pediatric Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Preoperative anxiety is common in children and is associated with emergence delirium—a distressing postoperative complication characterized by agitation and disorientation. Midazolam has long been the drug of choice for preoperative anxiolysis.
Anne Louise de Barros Garioud, Anwen Taplin, Yufei Shang, R. Nazim Khan, David Sommerfield, Neil Hauser, Aine Sommerfield, Britta S. von Ungern‐Sternberg   +7 more
wiley   +1 more source

Effects of different fractions of inspired oxygen on delayed neurocognitive recovery in patients with one-lung ventilation: a randomized clinical trial. [PDF]

Med Gas Res
Wu C, Zhang W, Lin J, Zhao D, Fang J.
europepmc   +1 more source