Results 51 to 60 of about 14,534,614 (293)

A structured narrative review of clinical and experimental studies of the use of different positive end‐expiratory pressure levels during thoracic surgery

open access: yesThe Clinical Respiratory Journal, 2022
Objectives This study aimed to present a review on the general effects of different positive end‐expiratory pressure (PEEP) levels during thoracic surgery by qualitatively categorizing the effects into detrimental, beneficial, and inconclusive.
Jiang Yueyi, Tan Jing, Gu Lianbing
doaj   +1 more source

C Arm confirmation of lung isolation in pediatric patients undergoing video-assisted thoracoscopic decortication: A retrospective case series

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2022
Video-assisted thoracoscopic surgery (VATS) is a frequently performed procedure in children which requires an efficient technique for lung isolation. Unavailability of appropriate size double-lumen tubes (DLT) for children and fiber optic scopes inspired
Vrushali Ponde   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Arterial oxygenation during one-lung ventilation: combined versus general anesthesia

open access: yes, 1999
The optimal anesthetic management of patients undergoing thoracotomy for pulmonary resection has not been definitely determined. We evaluated whether general i.v.
Garutti Martínez, Ignacio   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Effective ventilation strategies for one-lung ventilation [PDF]

open access: yes, 2022
For patients requiring mechanical ventilation during surgery, anesthesia practitioners generally choose between one of two approaches, lung-protective ventilation (LPV) or traditional individual parameter manipulation.
Kirkpatrick, Michael, Ledbetter, Maria
core  

One-lung ventilation for percutaneous thermal ablation of liver tumors in the hepatic dome

open access: yesInternational Journal of Hyperthermia, 2020
Purpose To investigate the feasibility, efficacy and safety of one-lung ventilation for percutaneous thermal ablation of liver tumors in the hepatic dome.
Yinglin Long   +8 more
doaj   +1 more source

Management of traumatic pneumothorax with massive air leakage: role of a bronchial blocker: a case report [PDF]

open access: yesKorean Journal of Anesthesiology, 2014
Massive air leakage through a lacerated lung produces inadequate ventilation and hypoxemia. Tube exchange from a single to double lumen endotracheal tube (DLT), and lung separation to maintain oxygenation, are challenging for seriously injured patients ...
Dong Kyu Lee   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Correlation between Preoperative Spirometry and Arterial Partial Oxygen Pressure during One-Lung Ventilation [PDF]

open access: yes, 2001
We evaluated the correlation between routine preoperative spirometry and PaOズduring one-lung ventilation (OLV)in 75 patients who underwent open chest surgery in the lateral position.PaOズat 30 minutes after the start of OLV showed the lowest value and ...
加藤, 幹芳   +3 more
core  

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