Results 141 to 150 of about 17,928,993 (286)
Ethical Treatment of Invasive and Native Fauna in Australia: Perspectives through the One Welfare Lens. [PDF]
Animals (Basel), 2022 Kennedy BPA +7 more
europepmc +1 more source
, 2015 Australia\u27s welfare 2015 is the 12th biennial welfare report of the Australian Institute of Health and Welfare. This comprehensive report provides an authoritative overview of the wellbeing of Australians, examining a wide range of relevant topics ...
Australian Institute of Health and Welfare
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Oregon Department of Human Services, Office of Child Welfare Programs, management staff
, 2013 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on November 26, 2014)"Last ...
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Animal Welfare and Farmers' Satisfaction in Small-Scale Dairy Farms in the Eastern Alps: A "One Welfare" Approach. [PDF]
Front Vet Sci, 2021 Spigarelli C +9 more
europepmc +1 more source
Immune-Enhancing Medicinal Plants: Are They a One Health, One Welfare Actor?
Medicinal plants have represented accessible and highly bioavailable remedies in traditional therapeutic and preventive practices of numerous populations worldwide. Veterinary treatments based on medicinal plants are also widespread, mainly targeting the control or prevention of parasitic diseases.
Aurel Vasiu +10 more
openaire +2 more sources
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source