Results 141 to 150 of about 483,490 (249)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

AI for One Welfare: the role of animal welfare scientists in developing valid and ethical AI-based welfare assessment tools. [PDF]

Front Vet Sci
Foris B, Sheng K, Dürnberger C, Oczak M, Rault JL.   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Animal welfare, human welfare. Putting one welfare in pig production into perspective

Human welfare and animal welfare and their environment are interdependent, leading to a new multidisciplinary scientific approach and the building of a global movement around these societal issues. In France, the RMT "One Welfare", a joint technology network, is working to put this concept into practice at the farm level.
Ramonet, Yannick, Boivin, Xavier
openaire   +1 more source

Temperament in Domestic Cats: A Review of Proximate Mechanisms, Methods of Assessment, Its Effects on Human-Cat Relationships, and One Welfare. [PDF]

Animals (Basel), 2020
Travnik IC, Machado DS, Gonçalves LDS, Ceballos MC, Sant'Anna AC.   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Natural Savanna Systems Within the "One Health and One Welfare" Approach: Part 2-Sociodemographic and Institution Factors Impacting Relationships Between Farmers and Livestock. [PDF]

Animals (Basel)
Romero MH, Gallego-Polania SA, Sanchez JA.   +2 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Review of the Online One Welfare Portal: Shared Curriculum Resources for Veterinary Undergraduate Learning and Teaching in Animal Welfare and Ethics. [PDF]

Animals (Basel), 2020
D McGreevy P, Fawcett A, Johnson J, Freire R, Collins T, Degeling C, Fisher AD, Hazel SJ, Hood J, Lloyd JKF, Phillips CJC, Stafford K, Hyde ML, Wilson B, Tzioumis V.   +14 more
europepmc   +1 more source