Results 81 to 90 of about 17,928,993 (286)

OTHER TITLE: Child Welfare System Task Force final report

open access: yes, 2019
At head of page O-1: Child Welfare System Task Force final report. "January 2019."Committee Reports to the Kansas Legislature ; 2019."House Sub. for SB 126 (2017) directs the Secretary for Children and Families to establish a Child Welfare System ...
Kansas Child Welfare System Task Force.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Situational Analysis of Attitudes toward Stray Cats and Preferences and Priorities for Their Management

open access: yesAnimals
Current cat management approaches are outdated and ineffective, failing to reduce stray cat numbers or related complaints and negatively impacting the job satisfaction and mental health of veterinary, shelter, and municipal staff.
Jacquie Rand   +5 more
doaj   +1 more source

Robust Multidimensional Welfare Comparisons: One Vector of Weights, One Vote [PDF]

open access: yesSSRN Electronic Journal, 2013
Many aspects of social welfare are intrinsically multidimensional. Composite indices at-tempting to reduce this complexity to a unique measure abound in many areas of economics and public policy. Comparisons based on such measures depend, sometimes critically, on how the different dimensions of performance are weighted. Thus, a policy maker may wish to
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Other title: Report of the chief juvenile court probation officer of the state of Connecticut for ...; Other title: Volume for 1940 has title: Connecticut children in court : the report of the Legislative Council of the state of Connecticut for the fiscal year ending ... and the calendar year ending ...

open access: yes, 1934
Annual; Report year varies; issue for calendar year ending 1940 includes fiscal year ending June 30, 1940.; Volumes for 1931-1933 issued by the Bureau of Child Welfare; volumes for 1934- by the Office of Commissioner of ...
Connecticut. Bureau of Child Welfare.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Other title: Report of the chief juvenile court probation officer of the state of Connecticut for ...; Other title: Volume for 1940 has title: Connecticut children in court : the report of the Legislative Council of the state of Connecticut for the fiscal year ending ... and the calendar year ending ...

open access: yes, 1933
Annual; Report year varies; issue for calendar year ending 1940 includes fiscal year ending June 30, 1940.; Volumes for 1931-1933 issued by the Bureau of Child Welfare; volumes for 1934- by the Office of Commissioner of ...
Connecticut. Bureau of Child Welfare.
core  

One Health – One Welfare – One Rights

open access: yes
The projected WHO Pandemic Agreement, as currently under negotiation, will most likely contain a detailed prescription of a One Health approach (Art. 1(d) and Art. 5 of the INB negotiating text of 30 October 2023). This contribution examines the legal potential of a One Health approach for laws and policies towards animals raised, kept, and slaughtered
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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