Results 41 to 50 of about 12,943,739 (316)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Using technologies to design personalized learning pathways as a part of scientific practice of students

open access: yesRUDN Journal of Informatization in Education, 2021
Problem and goal. The article deals with the process of designing the high school internship program of the ITMO Universitys Information Chemistry Center by using information and communications technology (ICT).
Elizaveta A. Osipovskaya   +2 more
doaj   +1 more source

Latinos Online [PDF]

open access: yes, 2007
Presents findings from a telephone survey conducted in 2006, and demonstrates that Hispanics with lower levels of education and English proficiency remain largely disconnected from the ...
Gretchen Livingston, Susannah Fox
core  

Online Matrix Completion and Online Robust PCA

open access: yes, 2015
This work studies two interrelated problems - online robust PCA (RPCA) and online low-rank matrix completion (MC). In recent work by Cand\`{e}s et al., RPCA has been defined as a problem of separating a low-rank matrix (true data), $L:=[\ell_1, \ell_2 ...
Lois, Brian, Vaswani, Namrata
core   +1 more source

Flat primes and thin primes [PDF]

open access: yes, 2010
A number is called upper (lower) flat if its shift by +1 ( −1) is a power of 2 times a squarefree number. If the squarefree number is 1 or a single odd prime then the original number is called upper (lower) thin. Upper flat numbers which are primes arise
Broughan, Kevin A., Zhou, Qizhi
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Content Creation Online [PDF]

open access: yes, 2004
Presents findings from surveys conducted between March and May 2003. Measures the extent to which American adults have used the Internet to publish their thoughts, respond to others, post pictures, and share ...
Amanda Lenhart   +2 more
core  

Fraternity and Equality [PDF]

open access: yes, 2013
Is there a connection between the values of fraternity and outcome equality? Is inequality at odds with fraternity? There are reasons to doubt that it is.
Geoffrey Cupit, Rawls
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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