Results 131 to 140 of about 141,371 (299)

A simplified online adaptive workflow for long-course magnetic resonance-guided radiotherapy in esophageal cancer

Physics and Imaging in Radiation Oncology
Background and Purpose: Online adaptive magnetic resonance-guided radiotherapy (MRgRT) enables high-precision radiotherapy for esophageal cancer patients but is less feasible due to long on-table times in combination with long-course treatment.
Koen M. Kuijer, Roel Bouwmans, Lando S. Bosma, Stella Mook, Gert J. Meijer   +4 more
doaj   +1 more source

Predicting optimal impact interventions in the post‐HPV vaccination world

International Journal of Cancer, EarlyView.
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen, Marc Lipsitch, Ville N. Pimenoff, Karin Sundström, Johannes Berkhof, Iacopo Baussano, Simopekka Vänskä, Joakim Dillner   +7 more
wiley   +1 more source

Markerless liver online adaptive stereotactic radiotherapy: feasibility analysisCervantes.

Physics in medicine and biology
Objective. Radio-opaque markers are recommended for image-guided radiotherapy in liver stereotactic ablative radiotherapy (SABR), but their implantation is invasive. We evaluate in thisin-silicostudy the feasibility of cone-beam computed tomography-guided stereotactic online-adaptive radiotherapy (CBCT-STAR) to propagate the target volumes without ...
Pierrard, Julien, Deheneffe, Stephanie, Dechambre, David, Sterpin, Edmond, Geets, Xavier, Van Ooteghem, Genevieve   +5 more
openaire   +2 more sources

Use of Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy for Oligometastatic Lung Adenocarcinoma: Leveraging CT-Guided Online Adaptive Radiotherapy

Cureus
Management of oligometastatic non-small cell lung cancer (OM-NSCLC) has changed considerably in recent years, as these patients were found to have better survival with systemic therapy followed by consolidative radiation. Stereotactic body radiotherapy (SBRT), characterized by high doses of radiation delivered in a limited number of fractions, has been
Eustace, Nicholas, Ladbury, Colton, Liu, Yufei, Amini, Arya, Sampath, Sagus, Watkins, Tyler, Tsai, Kevin, Maraghechi, Borna, Han, Chunhui, Shi, Chengyu, Liu, An, Williams, Terence, Lee, Percy   +12 more
openaire   +2 more sources

Patient‐ and caregiver‐reported barriers to chemotherapy in nine sub‐Saharan African countries: A cross‐sectional survey among population‐based registries

International Journal of Cancer, EarlyView.
What's New? Increasing cancer incidence and mortality in low‐ and middle‐income countries has heightened concerns about limited resources and barriers to care. This challenge is particularly urgent in Sub‐Saharan Africa (SSA), where cancer rates are rising sharply. Here, data from population‐based cancer registries in nine SSA countries was assessed to
Tamara König, Nikolaus Christian Simon Mezger, Ole Stoeter, Phoebe Mary Amulen, Margaret Borok, Gladys C. Chesumbai, Moudiongui MBoungou Dimitry, Ima‐Obong Ekanem, Adugna Fekadu, Bakarou Kamaté, William Muller, Alex Alain Kabena Nzambikolo, Abidemi Omonisi, Furaha Serventi, Markus Wallwiener, Biying Liu, Donald Maxwell Parkin, Pablo Sandro Carvalho Santos, Eva Johanna Kantelhardt, Eric Sven Kroeber   +19 more
wiley   +1 more source

CBCT-Based Online Adaptive, Ultra-Hypofractionated Radiotherapy for Prostate Cancer: First Clinical Experiences

Medicina
Background and Objectives: Ultra-hypofractionated radiotherapy (uhRT) is increasingly used for low- and intermediate-risk localized prostate cancer, necessitating exceptional precision compared to conventional fractionation.
Georg Wurschi, Alexander Voigt, Noreen Murr, Cora Riede, Michael Schwedas, Maximilian Römer, Sonia Drozdz, Klaus Pietschmann   +7 more
doaj   +1 more source

Development and psychometric properties of a general cancer stigma scale

International Journal of Cancer, EarlyView.
What's New? Cancer‐related stigma can fuel anxiety and depression and lead to self‐isolation, delayed treatment, and decreased quality of life. The extent to which stigma impacts cancer patients, however, remains uncertain. This study applied mixed methods in high‐ and low‐income settings, with cohorts in the U.S. state of Utah and Lilongwe, Malawi, to
Stephen M. Kimani, Gita Suneja, Agatha Bula, Chaorong Wu, Abhilasha Khatri, Nehal Bakshi, Olivia R. Hanson, Aparna Mangadu, Mercy Tsidya, Melissa A. Stockton, Brandon A. Knettel, Melissa H. Watt   +11 more
wiley   +1 more source

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

Feasibility of quantitative relaxometry for prostate target localization and response assessment in magnetic resonance-guided online adaptive stereotactic body radiotherapy

Physics and Imaging in Radiation Oncology
Purpose: Multiparametric magnetic resonance imaging (MRI) is known to provide predictors for malignancy and treatment outcome. The inclusion of these datasets in workflows for online adaptive planning remains under investigation.
Ergys Subashi, Eve LoCastro, Sarah Burleson, Aditya Apte, Michael Zelefsky, Neelam Tyagi   +5 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source