Results 21 to 30 of about 141,371 (299)

Laser-free pelvic alignment in an online adaptive radiotherapy environment [PDF]

Technical Innovations & Patient Support in Radiation Oncology, 2020
The MR-Linac (MRL) provides a novel treatment modality that enables online adaptive treatments, but also creates new challenges for patient positioning in a laser-free environment. The accuracy and duration of prostate patient set-up on the MRL using two
Helen Barnes, Jonathan Mohajer, Alex Dunlop, Gillian Adair Smith, Trina Herbert, Rebekah Lawes, Alison Tree, Helen McNair   +7 more
doaj   +4 more sources

Clinical Implementation of PSMA-PET Guided Tumor Response-Based Boost Adaptation in Online Adaptive Radiotherapy for High-Risk Prostate Cancer. [PDF]

Cancers (Basel)
Simple Summary High-risk prostate cancer is difficult to treat because tumors are often large and close to sensitive organs such as the bladder and rectum.
Li R, Lin MH, Nguyen NC, Su FC, Parsons D, Salcedo E, Phillips E, Domal S, Garant A, Hannan R, Yang D, Afaq A, Lee M, Oz OK, Desai N.   +14 more
europepmc   +2 more sources

To irradiate or to wait: practical considerations when planning for stereotactic radiosurgery for kidney tumors using magnetic resonance-guided online adaptive radiotherapy. [PDF]

Radiat Oncol J
Radiotherapy (RT) is rapidly evolving due to the advances in radiation delivery and image-guidance technologies. The integration of magnetic resonance imaging (MRI) with linear accelerators has resulted in the most advanced type of image-guided RT, and ...
Kim JW.
europepmc   +2 more sources

Moderately hypofractionated online adaptive radiotherapy (SWIFT-1) in cervical cancer patients: study protocol for a multi-centered, open-label, two-arm, phase III, randomized controlled study. [PDF]

Radiat Oncol
External beam radiotherapy (EBRT) is an essential component of standard treatment for locally advanced cervical cancer. Moderately hypofractionated radiotherapy (MHRT) offers the potential to reduce treatment burden while compromising efficacy.
Zeng Z, Chen Y, Qiu J, Yang B, Wang Z, Meng X, Sun Y, Yan J, Hu K, Zhang F.   +9 more
europepmc   +2 more sources

ROAR-A: re-optimization based Online Adaptive Radiotherapy of anal cancer, a prospective phase II trial protocol

BMC Cancer
Background Chemo-radiotherapy with curative intent for anal cancer has high complete remission rates, but acute treatment-related gastrointestinal (GI) toxicity is significant. Toxicity occurs due to irradiation of surrounding normal tissue.
Katrine Smedegaard Storm, Lina M Åström, Patrik Sibolt, Claus P Behrens, Gitte F Persson, Eva Serup-Hansen   +5 more
doaj   +2 more sources

Simulation-Omitting and Using Library Patients for Pre-Planning Online Adaptive Radiotherapy (SUPPORT): A Feasibility Study for Spine Stereotactic Ablative Radiotherapy (SAbR) Patients. [PDF]

Cancers (Basel)
Simple Summary This standard radiation therapy workflow requires CT simulation and treatment planning before initiating treatments, which typically takes one to two weeks. This study explores a new approach to treating spine SAbR patients more quickly by
Wang D, Kim H, Zhuang T, Visak JD, Cai B, Parsons DDM, Jiang S, Godley AR, Lin MH.   +8 more
europepmc   +2 more sources

CBCT-based online adaptive radiotherapy of the prostate bed: first clinical experience and comparison to nonadaptive conventional IGRT. [PDF]

Strahlenther Onkol
Conventional image-guided radiotherapy (IGRT) of the prostate bed is challenged by the varying anatomy due to dynamic changes of surrounding organs such as the bladder and rectum. This leads to changed dose coverage of target and surrounding tissue.
Fischer J, Fischer LA, Bensberg J, Bojko N, Bouabdallaoui M, Frohn J, Hüttenrauch P, Tegeler K, Wagner D, Wenzel A, Schmitt D, Guhlich M, Leu M, El Shafie R, Stamm G, Schilling AF, Dröge LH, Rieken S.   +17 more
europepmc   +2 more sources

Adaptive margins for online adaptive radiotherapy [PDF]

Physics in Medicine & Biology, 2022
Abstract Objective. In online adaptive radiotherapy a new plan is generated every fraction based on the organ and clinical target volume (CTV) delineations of that fraction. This allows for a planning target volume margin that does not need to be constant over the whole course of treatment, as is the case in ...
Erik van der Bijl, Peter Remeijer, Jan-Jakob Sonke, Uulke A van der Heide, Tomas Janssen   +4 more
openaire   +4 more sources

Automatic AI-based contouring of prostate MRI for online adaptive radiotherapy

Zeitschrift für Medizinische Physik
Background and purpose: MR-guided radiotherapy (MRgRT) online plan adaptation accounts for tumor volume changes, interfraction motion and thus allows daily sparing of relevant organs at risk.
Marcel Nachbar, Monica lo Russo, Cihan Gani, Simon Boeke, Daniel Wegener, Frank Paulsen, Daniel Zips, Thais Roque, Nikos Paragios, Daniela Thorwarth   +9 more
doaj   +4 more sources

Full daily re-optimization improves plan quality during online adaptive radiotherapy

Physics and Imaging in Radiation Oncology
Background and purpose: Daily online treatment plan adaptation requires a fast workflow and planning process. Current online planning consists of adaptation of a predefined reference plan, which might be suboptimal in cases of large anatomic changes. The
Benjamin Tengler, Luise A. Künzel, Markus Hagmüller, David Mönnich, Simon Boeke, Daniel Wegener, Cihan Gani, Daniel Zips, Daniela Thorwarth   +8 more
doaj   +3 more sources