Results 161 to 170 of about 519,420 (310)

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang   +8 more
wiley   +1 more source

Més enllà de la usabilitat : característiques mínimes exigibles per a les interfícies de bases de dades web

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2004
Aquest treball pretén contribuir a l’establiment de directrius específiques d’usabilitat i de continguts informatius mínims, dirigides als dissenyadors d’interfícies web de consulta de bases de dades documentals.
Rodríguez Yunta, Luis   +1 more
doaj  

Ranking the Research Productivity of LIS Faculty and Schools: An Evaluation of Data Sources and Research Methods [PDF]

open access: yes, 2005
This study evaluates the data sources and research methods used in earlier studies to rank the research productivity of Library and Information Science (LIS) faculty and schools. In doing so, the study identifies both tools and methods that generate more
Spurgin, Kristina M., Meho, Lokman I.
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Más allá de la usabilidad : características mínimas exigibles para las interfaces de bases de datos web

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2004
Este trabajo intenta contribuir al establecimiento de directrices específicas de usabilidad y contenidos informativos mínimos, dirigidas a los diseñadores de interfaces web de consulta de bases de datos documentales.
Rodríguez Yunta, Luis   +1 more
doaj  

A Mexican case study for world water online

open access: yes, 2012
textWorld Water Online is a global system of hydrologic data. It is an integration of geospatial and temporal information across spatial scales: global, national, regional and local.
Espinoza Dávalos, Gonzalo Enrique
core  

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