Results 51 to 60 of about 4,196,888 (278)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Planetary Health Booms: Unpacking the Surge in Research Across the Globe Through Joint‐Point Analysis

open access: yesGeoHealth
Planetary Health (PH) is a relatively new field that studies the sciences behind the interaction between the environment, living organisms, and human health. The number of publications in this field has increased exponentially in the past few years. This
Gladson Vaghela   +7 more
doaj   +1 more source

How teachers interpret displays of students’ gaze in reading comprehension assignments

open access: yesFrontline Learning Research, 2021
Reading comprehension is a central skill in secondary education. To be able to provide adaptive instruction, teachers need to be able to accurately estimate students’ reading comprehension. However, they tend to experience difficulties doing so.
Carolien A. N. Knoop-van Campen   +6 more
doaj   +1 more source

Learning in MOOCs: The [Un]democratisation of Learning [PDF]

open access: yes, 2017
Massive open online courses have been signaled as a disruptive and democratizing force in online, distance education. This position paper critiques these claims, examining the tensions between viewing MOOCs as products and students as customers, and the ...
Hood, Nina, Littlejohn, Allison
core  

Falling through the (cultural) gaps? [PDF]

open access: yes, 2004
In this paper we report findings of a study of online participation by culturally diverse participants in a distance adult education course offered in Canada, and examine two of the study’s early findings.
Chase, Mackie   +5 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Two Dreams, One Degree [PDF]

open access: yes, 2017
After a long night of body checks, slapshots and chasing a puck up and down the ice, Michael McCurtain ’16 often retreated to his hotel room – to tackle accounting homework.
Davis, Laura
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

STUDENTS' PERSPECTIVES ON THE QUALITY OF DISTANCE LEARNING MATERIALS IN SELECTED HIGHER EDUCATION INSTITUTIONS IN ETHIOPIA [PDF]

open access: yesSocial Sciences and Education Research Review
Successful Open and Distance Learning relies on well-developed Self-Instructional Materials, crucial for facilitating self-directed learning. Effective self-instructional materials convey knowledge, motivate learners, and reduce the need for extensive ...
Tessema Aderajew, Mapheleba Lekhetho
doaj   +1 more source

Academic professional development for effective e-learning: a possible framework for Brazil [PDF]

open access: yes, 2007
Distance education at a tertiary level in Brazil represents a very new educational approach compared with countries such as Australia and the United Kingdom.
Bossu, Carina, Smyth, R, Stein, S
core   +1 more source

Home - About - Disclaimer - Privacy