Results 51 to 60 of about 4,235,597 (300)

Planetary Health Booms: Unpacking the Surge in Research Across the Globe Through Joint‐Point Analysis

open access: yesGeoHealth
Planetary Health (PH) is a relatively new field that studies the sciences behind the interaction between the environment, living organisms, and human health. The number of publications in this field has increased exponentially in the past few years. This
Gladson Vaghela   +7 more
doaj   +1 more source

Interactive learning online: Challenges and opportunities [PDF]

open access: yes, 2012
Since the early 1990s online education and online learning systems have held the promise of increasing instructional productivity and reducing costs without sacrificing educational quality. There is no evidence to date that such promise has materialized.
Rutherford, Becky   +2 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Web 2.0 Use in Higher Education

open access: yesEURODL, 2015
This study analyzed current uses of emerging Web 2.0 technologies in higher education with the intent to better understand which tools teachers are using in the classroom. A total of 189 faculty in higher education from three western US universities were
Michelle Rogers-Estable
doaj   +1 more source

Preparing Higher Education Tutors for Delivering Online Courses [PDF]

open access: yes, 2015
This paper identifies that academic staff need to be suitably prepared to deliver wholly online courses, and outlines the steps taken towards achieving this, at one Higher Education institution in the UK. E-learning, whether partially (blended) or wholly
Allen, Jessica   +3 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Framing student engagement in higher education [PDF]

open access: yes, 2013
This is an Accepted Manuscript of an article published by Taylor & Francis in Studies in Higher Education on 2011, available online: https://www.tandfonline.com/doi/full/10.1080/03075079.2011 ...
Kahu, ER
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

How teachers interpret displays of students’ gaze in reading comprehension assignments

open access: yesFrontline Learning Research, 2021
Reading comprehension is a central skill in secondary education. To be able to provide adaptive instruction, teachers need to be able to accurately estimate students’ reading comprehension. However, they tend to experience difficulties doing so.
Carolien A. N. Knoop-van Campen   +6 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

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