Results 31 to 40 of about 107,193 (298)
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Современные информационные технологии и IT-образованиеThe article expounds practical aspects of carrying different educational events within the framework of attracting a new audience to the Russian online encyclopedia Ruwiki and popularizing work with the encyclopedic format of information delivery ...
Natalia Senatorova
doaj +1 more source
A blockchain-enabled wiki framework based on participatory design
Digital Communications and Networks, 2022 The 5G mobile Internet facilitates contents generation for online communities and platforms through human-to-human collaboration. Wikipedia, a well-known online community, uses wiki technology to build an encyclopedia through collective intelligence and ...
Zheng Xu +4 more
doaj +1 more source
Advanced Science, EarlyView.This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu +9 more
wiley +1 more source
Creation of a Regional Edition of Ruwiki (a Case of the Komi-Language Edition)
Современные информационные технологии и IT-образованиеThe article is devoted to an analytical description of the creation of a regional edition of the new online encyclopedia Ruwiki. The combination of the latest digital and language technologies with 20 languages of the peoples of Russia determines the ...
Marina Fedina
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Knowledge Management in Railway Industry: A Conceptual Model Based on Open Innovation and online Communities [PDF]
International Journal of Railway Research, 2019 Organizations need to be capable of attracting external knowledge. This activity is extremely related to innovation process and particularly to open innovation approach.
Majid Babaei Ebrahimabadi +2 more
doaj
Ten years of CAZypedia::A living encyclopedia of carbohydrate-active enzymes [PDF]
, 2018 CAZypeia was initiated in 2007 to create a comprehensive, living encyclopedia of the carbohydrate-active enzymes (CAZymes) and associated carbohydrate-binding modules involved in the synthesis, modification, and degradation of complex carbohydrates ...
core +1 more source
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
CHIMIA, 2010 The chemistry encyclopedia Römpp Online and the German universal encyclopedia Wikipedia were assessed by first-year university students on the basis of a set of 30 articles about chemical thermodynamics.
Lukas Korosec +3 more
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Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source