Results 31 to 40 of about 97,057 (258)
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Advanced Science, EarlyView.Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
CHIMIA, 2010 The chemistry encyclopedia Römpp Online and the German universal encyclopedia Wikipedia were assessed by first-year university students on the basis of a set of 30 articles about chemical thermodynamics.
Lukas Korosec +3 more
doaj +1 more source
Advanced Science, EarlyView.The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen +9 more
wiley +1 more source
Studia Lexicographica, 2023 The aim of this article is to present the Encyclopedia of Modern Ukraine (Ukrainian: Entsyklopediia Suchasnoi Ukrainy) as one of the priority Ukrainian academic scholarly publications in the context of the ongoing Russian war against Ukraine, and to ...
Mykola Zhelezniak, Oleksandr Ishchenko
doaj
Advanced Science, EarlyView.Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang +11 more
wiley +1 more source
Advanced Science, EarlyView.We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen +5 more
wiley +1 more source
Academic online encyclopedias in view of the recent information space developing
Енциклопедичний Вісник України, 2018 The article describes the phenomenon of the electronic encyclopedia activity and investigates the electronic Internet encyclopedias created by the institutions of the National Academy of Sciences of Ukraine.
Mykola Zhelezniak, Oleksandr Ishchenko
doaj +1 more source
Requirements Compilation for Building Formal Ultra-time Team, for Imam Ali (AS) Online Encyclopedia Development [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2018 Purpose: Ultra-time teams, being capable of conducting great and long-term deeds, have significant impact on the development of production capacity and knowledge management.
Ali asghar Pourezzat +2 more
doaj +1 more source
Advanced Science, EarlyView.Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku +4 more
wiley +1 more source
Universal Encyclopedic Platform for Working with Knowledge
Современные информационные технологии и IT-образование, 2023 The rapid escalation of digital expanse, covering the entire life of modern society, is accompanied by an explosive growth in information flows. This process especially affects the educational environment, for which the exchange of information is the ...
Alexei Semenov +5 more
doaj +1 more source