Results 101 to 110 of about 19,286 (280)

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

Ask Them—They’ll Tell You! Eliciting Student Perspectives to Improve Services [PDF]

, 2011
Most people avoid doing qualitative research because they think it is not scientifically rigorous and requires time and lots of money. In fact, there is a lot one can do with little overhead that reaps immediate benefits for improving services and ...
Valentine, Barbara
core   +1 more source

Measuring the Popularity of Job Skills in Recruitment Market: A Multi-Criteria Approach

, 2017
To cope with the accelerating pace of technological changes, talents are urged to add and refresh their skills for staying in active and gainful employment. This raises a natural question: what are the right skills to learn?
Li, Pan, Xiong, Hui, Xu, Tong, Zhu, Chen, Zhu, Hengshu   +4 more
core   +1 more source

Microbial influences on immune modulation and colorectal cancer progression through combined transcriptomic and microbiomic analysis

iMetaOmics, EarlyView.
Schematic representation of the distinct tumor microenvironment characteristics in CA1 and CA2 subtypes. CA1 illustrates an immune‐active tumor microenvironment characterized by elevated infiltration of immune cells, particularly CD8 + T cells and macrophages, and enhanced IFN‐γ signaling.
Shuting Xia, Likun Wang, Yangzhuo Xu, Jiaqi Zhang, Zeyang Zhou, Libing Sun, Heng Li, Chungen Xing, Jialu Mao, Yina Liu, Fulin Yang, Ling Zhong, Jiancheng Xu, Xiaodong Yang, Zhemin Zhou   +14 more
wiley   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

iMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang, Lanmei Yin, Zhaobin Wang, Jun Li, Xianglin Zeng, Qiye Wang, Jianzhong Li, Kang Xu, Huansheng Yang, Yulong Yin   +9 more
wiley   +1 more source

Meta‐Virtuality: Strategies of Disembeddedness in Virtual Interiorities

Journal of Interior Design, EarlyView., 2022
ABSTRACT To reclaim their seat in the rapidly growing market of virtual space, designers of the built environment can benefit from reevaluating theories that see the virtual as a mere extension/reflection of the physical. By claiming ontological autonomy from external worlds, the virtual is liberated from the hegemonic control of the physical.
Vahid Vahdat
wiley   +1 more source

The role of the gut microbiome in the regulation of high‐altitude adaptation

iMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang, Senlin Zhu, Michael Kreuzer, Shoukun Ji, Wei Wang, Yanliang Bi, Shengli Li   +6 more
wiley   +1 more source

Automated Generation of Multiple-Choice Questions for Computer Science Education Using Conditional Generative Adversarial Networks

IEEE Access
This work presents a novel perspective towards generating automated multiple-choice questions (MCQs)-a task fundamentally different due to the highly dynamic nature of computer science education, which spans several sub-domains.
Muhammad Shoaib, Ghassan Husnain, Nasir Sayed, Yazeed Yasin Ghadi, Masoud Alajmi, Ayman Qahmash   +5 more
doaj   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

User Attitudes on E-Books Collection in Mahatma Gandhi University Library: A Case Study [PDF]

, 2012
A study on the user’s attitudes, interest and understanding of e-book collections. The sample taken for the study is the E-book collection developed at the Mahatma Gandhi University Library and its users.
Jasimudeen, S., Jose Mathew,, Maghesh Rajan, M.   +2 more
core