Results 51 to 60 of about 1,012,506 (332)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

E-Commerce of China: its Reasons for Success and Current Development Trends

open access: yesЦифровая трансформация, 2023
E-commerce is one of the highly digitalized industries, which quickly changes the way people buy products and use companies’ services. There are many countries in the world economy now that are trying to adapt informational and communication technologies
A. A. Vlasenko, G. G. Goloventchik
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The Effects of Popularity: An Online Store Perspective

open access: yesInternational Journal of Information Science and Management, 2014
Recently, internet is widely used in our daily life, caused online customer growing rapidly, then the amount of online store rising quickly. Therefore, it is an important issue for online stores to stand out from the crowd, even boost sales and profit ...
Ching-Chuan Lin, Te-King Chien
doaj  

Aspect-Based Sentiment Analysis of Online Marketplace Reviews Using Convolutional Neural Network

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2020
Most online stores provide product review facilities that contain responses to a product. The number of reviews makes it difficult for potential customers to make conclusions, so that sentiment analysis is needed to extract information from these reviews.
MHD Theo Ari Bangsa   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

CONSUMER DEMAND: ONLINE OR RETAIL STORES

open access: yesECONOMICS AND MANAGEMENT, 2014
Consumers’ interest in online trade increases constantly. Therefore, this paper addresses issues of such kind. The study presented contains the following aspects. First, consumer choice models are analysed in the paper. Second, the factors, which describe consumer choice between the online and retail stores, are determined through literature analysis ...
Burinskienė, Aurelija   +1 more
openaire   +3 more sources

Verkkokaupan rakentaminen pienyritykselle [PDF]

open access: yes, 2013
Tässä opinnäytetyössämme tavoitteena oli rakentaa verkkokauppa Natural Beautylle ottamalla huomioon toimeksiantajan toiveet ja tarpeet. Toteutettavan verkkokaupan kriteerinä oli sen helppokäyttöisyys sekä asiakkaille että ylläpitäjälle.
Määttä, Kati, Yliherva, Kaija
core  

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