Results 61 to 70 of about 1,015,894 (300)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Retail Online Kirana Stores

open access: yesIndian Journal of Science and Technology, 2016
Background of the Study: Internet has tremendously changed the face of business arena including e-commerce. Till recent times, ecommerce is confined to only few services like airline tickets, railway tickets, hotel bookings, online mobile recharge etc. Recently E-commerce is emerged into retail and moreover kirana sector also. Objectives of the Study:
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Unwillingness to Pay for Privacy: A Field Experiment [PDF]

open access: yes
We measure willingness to pay for privacy in a field experiment. Participants were given the choice to buy a maximum of one DVD from one of two online stores.
Alastair R. Beresford   +2 more
core   +3 more sources

Undergraduate students: interactive, online experiences and ePortfolio development [PDF]

open access: yes, 2011
Results of a previous study by the authors into the perceived value and potential of ePortfolios to assist undergraduate students indicated that technology was an important aspect of their everyday lives.
Beresford, Wendy, Cobham, David
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Less or More: Managing Channel Inventory and Store Service Strategies for Omnichannel Retailing

open access: yesJournal of Theoretical and Applied Electronic Commerce Research
Retailers must reevaluate store positioning when implementing omnichannel strategies. This study examines retailers’ strategic preferences toward in-store services, including Buy-Online-Pickup-in-Store (BOPS), Buy-Online-Return-in-Store (BORS), and their
Fangfang Ma   +3 more
doaj   +1 more source

A Decision Model for E-commerce-enabled Partial Market Exit [PDF]

open access: yes, 2010
Struggling retail chains often try to recover profitability by closing some of their stores. The challenge in this strategy lies in determining how many stores to close, as store exit has implications for both the customers and the supply chain.
Bhatnagar, Amit, Syam, Siddhartha
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Pengaruh Kualitas Layanan Toko Terhubung Terhadap Kepuasan dan Loyalitas Pelanggan

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2013
The study aims to examine the relationship between buying environment characteristics, esatisfaction and e-loyalty referring to the research model from Kim et al. (2009) that is applied to apparel product category in the US as a developed country.
Muhammad Febri Hardiansyah   +1 more
doaj  

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