Results 51 to 60 of about 1,549,872 (314)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Comparative evaluation of research vs. Online MT systems [PDF]
, 2011 This paper reports MT evaluation experiments that were conducted at the end of year 1 of the EU-funded CoSyne 1 project for three language combinations, considering translations from German, Italian and Dutch into English.
Toral, Antonio +3 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2017 The objective of this work is to address, from the educational perspective, the trends in the software engineerring discipline, which rely on a significant increase in the use of remotely accessible and remotely controlled embedded devices.
Janusz Zalewski +3 more
core +1 more source
Znet: Deep Learning Approach for 2D MRI Brain Tumor Segmentation
IEEE Journal of Translational Engineering in Health and Medicine, 2022 Background: Detection and segmentation of brain tumors using MR images are challenging and valuable tasks in the medical field. Early diagnosing and localizing of brain tumors can save lives and provide timely options for physicians to select efficient ...
Mohammad Ashraf Ottom +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Investigating website usability and behavioural intention for online hotel reservations: a cognitive perspective [PDF]
, 2014 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The problem area identified for this research is to define the cognitive factors and Customers’ Critical Information Requirements (CCIRs) that affect the ...
Drousiotou, Vryona
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
SensorsIndoor localization of a mobile target represents a prominent application within wireless sensor network (WSN), showcasing significant values and scientific interest.
Rihab Souissi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source