Results 41 to 50 of about 4,617,678 (304)

Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients. [PDF]

, 2014
BackgroundGender-based differences in disease onset in murine models of malignant peripheral nerve sheath tumor (MPNST) and in patients with Neurofibromatosis type-1-(NF-1)-associated or spontaneous MPNST has not been well studied.MethodsForty-three ...
Dry, Sarah M, Eilber, Fritz C, Federman, Noah, Li, Yunfeng, Nakashima, Jonathan, Shurell, Elizabeth, Smith, Kathleen B, Tam, Brenna M, Tap, William D, Tran, Linh M, Wu, Hong   +10 more
core   +2 more sources

Young-Onset Dementia [PDF]

Seminars in Neurology, 2013
Young-onset dementia is a neurologic syndrome that affects behavior and cognition of patients younger than 65 years of age. Although frequently misdiagnosed, a systematic approach, reliant upon attainment of a detailed medical history, a collateral history, neuropsychological testing, laboratory studies, and neuroimaging, may facilitate earlier and ...
Dulanji K, Kuruppu, Brandy R, Matthews
openaire   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

ENabling VISions And Growing Expectations (ENVISAGE): Co-development and feasibility of an “integrated” version of ENVISAGE for service providers and parents of children with neurodevelopmental disabilities

Pilot and Feasibility Studies
Introduction This paper reports on the first two phases of a three-phase project to develop and evaluate an “integrated” iteration of ENabling VISions And Growing Expectations (ENVISAGE).
Alice Kelen Soper, Marilyn Wright, Elizabeth Chambers, Debra Hughes, Marion Knutson, Kim Hesketh, Jessica Hanson, Myanca Rodrigues, Andrea Cross, Christine Imms, Rose Babic, Bridget O’Connor, Michelle Phoenix, Sandra Moll, Peter Rosenbaum   +14 more
doaj   +1 more source

Onset of $\eta$ nuclear binding

, 2017
Recent studies of $\eta$ nuclear quasibound states by the Jerusalem-Prague Collaboration are reviewed, focusing on stochastic variational method self consistent calculations of $\eta$ few-nucleon systems.
Barnea, Nir, Bazak, Betzalel, Cieplý, Aleš, Friedman, Eliahu, Gal, Avraham, Mareš, Jiří, Schäfer, Martin   +6 more
core   +1 more source

EMG Onset Timing [PDF]

Physical Therapy, 1998
To the Editor: I read the recent report by Gilleard and colleagues (January 1998) with great interest, in the hope that the study would shed more light on the issue of relative timing of vastus medialis oblique muscle (VMO) and vastus lateralis muscle (VL) electromyographic (EMG) activity during voluntary activation.
openaire   +2 more sources

ASSESSMENT OF COLOR VISION FOR DIAGNOSIS AND DYNAMIC MONITORING OF MULTIPLE SCLEROSIS

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Multiple sclerosis is regarded as the most frequent cause of neurological disability. Visual disturbances are common and may be due to pathology of retina, optic nerve and cerebral conduction tracts (optic tract).
N. V. Kuchina, T. I. Yakushina, S. V. Kotov, D. G. Lapitan, O. M. Andryukhina, A. A. Ryabtseva   +5 more
doaj   +1 more source

Performance of CMIP6 HighResMIP on the Representation of Onset and Cessation of Seasonal Rainfall in Southern West Africa

Atmosphere, 2022
Changes in rainfall onset and cessation dates are critical for improving decision making and adaptation strategies in numerous socio-economic sectors. An objective method of determining onset and cessation date is employed over Southern West Africa (SWA)
Francis Nkrumah, Kwesi Akumenyi Quagraine, Kwesi Twentwewa Quagraine, Caroline Wainwright, Gandomè Mayeul Leger Davy Quenum, Abraham Amankwah, Nana Ama Browne Klutse   +6 more
doaj   +1 more source

Repeated crystallization in undercooled Zr41Ti14Cu12Ni10Be23 liquids [PDF]

, 2000
Isothermal crystallization studies are performed on Zr41Ti14Cu12Ni10Be23 melts. Undercooling experiments are carried out repeatedly at 907, 860, and 750 K. The scattering of the time to reach the onset of crystallization is investigated.
Busch, Ralf, Johnson, William L., Schroers, Jan   +2 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source