Results 41 to 50 of about 963,742 (255)

Total neoadjuvant therapy in early-onset versus average-onset locally advanced rectal cancer: patient characteristics and tolerance of therapy☆

ESMO Gastrointestinal Oncology
Background: Patients with early-onset (EO, age
M.L. Conces, N. Tursun, I. Ozgur, S. Yilmaz, D. Elamin, S. Patil, Y. Bouferraa, E. Gorgun, D. Liska, E. Weinstein, S.D. Kamath, S.R. Steele, A.A. Khorana, B. Laderian, T.T. Jayakrishnan, K.G. Nair, S.R. Amarnath, E.H. Balagamwala, B.N. Estfan, H. Kessler, M.J. McNamara, M.A. Shapiro, M.A. Valente, S.S. Krishnamurthi   +23 more
doaj   +1 more source

Resolving Seasonal Ice Velocity of 45 Greenlandic Glaciers With Very High Temporal Details

Geophysical Research Letters, 2019
Seasonal glacier ice velocities are important for understanding controlling mechanisms of ice flow. For many Greenlandic glaciers, however, these measurements are limited by low temporal resolution.
Saurabh Vijay, Shfaqat Abbas Khan, Anders Kusk, Anne M. Solgaard, Twila Moon, Anders Anker Bjørk   +5 more
doaj   +1 more source

More Than Spikes: On the Added Value of Non-linear Intracranial EEG Analysis for Surgery Planning in Temporal Lobe Epilepsy

Frontiers in Neurology, 2022
Epilepsy surgery can be a very effective therapy in medication refractory patients. During patient evaluation intracranial EEG is analyzed by clinical experts to identify the brain tissue generating epileptiform events.
Michael Müller, Martijn Dekkers, Roland Wiest, Kaspar Schindler, Christian Rummel   +4 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Correspondence of Consonant Clustering with Particular Vowels in German Dialects

Languages
Recent work found a correspondence between consonant clustering probability in monosyllabic lexemes and the three vowel types, short and long monophthong and diphthong, in German dialects. Furthermore, that correspondence was found to be bound to a North–
Samantha Link
doaj   +1 more source

A rapid-onset diffusion functional MRI signal reflects neuromorphological coupling dynamics

NeuroImage, 2021
Functional Magnetic Resonance Imaging (fMRI) has transformed our understanding of brain function in-vivo. However, the neurovascular coupling mechanisms underlying fMRI are somewhat “distant” from neural activity.
Daniel Nunes, Rita Gil, Noam Shemesh
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

An examination of the association between early initiation of substance use and interrelated multilevel risk and protective factors among adolescents.

PLoS ONE, 2019
One of the major goals of drug use prevention programs is to delay the age of onset of substance use. What is called early initiation, usually occurring in adolescents under the age of 15, is a salient predictor of Substance Use Disorders later in ...
Carlos Andres Trujillo, Diana Obando, Angela Trujillo   +2 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Aerosol-induced effects on pre- and developed Indian summer monsoon and the corresponding onset and withdrawal

, 2023
Abstract The NCAR Community Earth System Model is used to study aerosol direct effect on Indian summer monsoon (ISM). We perform two sets of 30-year simulations subject to prescribed perpetual SST annual cycle: CTL and AERO. The two differ by anthropogenic emissions over Indian Peninsula that is included in AERO.
Kuan-Tzu Huang, Chung-Hsiung Sui, Min-Hui Lo, Yu-Yang Kuo, Chiung-Wen June Chang   +4 more
openaire   +1 more source