Results 71 to 80 of about 2,455,480 (298)

Episodic Visual Hallucinations, Inference and Free Energy

Entropy
Understandings of how visual hallucinations appear have been highly influenced by generative approaches, in particular Friston’s Active Inference conceptualization.
Daniel Collerton, Ichiro Tsuda, Shigetoshi Nara   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Announcement of Correspondence Courses [PDF]

, 1937
Correspondence bulletinMonthly bulletin containing information on distance education courses offered by the departments of Texas State College for Women.
Texas State College for Women (Denton, Tex.)
core   +1 more source

Effects of dynamical quark flavors on imaginary potential and thermal width in heavy quarkonium from AdS/CFT correspondence

Physics Letters B
In this work, we investigate the unquenched effects on the imaginary potential and thermal width within the framework of the AdS/CFT correspondence. Using the Nambu-Goto action, we find that the imaginary potential vanishes in the quenched system (Nf=0 ...
Jing Zhou, Saiwen Zhang, Menjun Zhu
doaj   +1 more source

Influence of mental stress on the pulse wave features of photoplethysmograms

Healthcare Technology Letters, 2019
Mental stress is a major burden for our society. Invasive and non-invasive methods have been proposed to monitor and quantify it using various sensors on and off body.
Patrick Celka, Peter H. Charlton, Peter H. Charlton, Bushra Farukh, Bushra Farukh, Philip Chowienczyk, Jordi Alastruey   +6 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Functional near-infrared spectroscopy pre-ictal oscillations recorded simultaneously with stereo-EEG

NeuroImage: Reports
Background: Peri-ictal hemodynamic alterations have been consistently demonstrated using functional near-infrared spectroscopy (fNIRS). However, whether ultra-slow hemodynamic activity develops before intracranially defined seizure onset remains ...
Netaniel Rein, Revital Shechter, Yael Avni, Evgeny Tsizin, Oshrit Arviv, Dana Ekstein, Tal Benoliel, Diya Doufish, Tal Gilboa, Naomi Froimovich, Yuliya Katz, Paz Har-Shai Yahav, Guy Rosenthal, Sami Heymann, Zvi Israel, Michal Balberg, Mordekhay Medvedovsky   +16 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source