Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Unraveling the Genetic Heartbeat: Decoding Cardiac Involvement in Duchenne Muscular Dystrophy
Cardiomyopathy represents the most important life-limiting condition of Duchenne muscular dystrophy (DMD) patients after the age of 20. Genetic alterations in the DMD gene result in the absence of functional dystrophin protein, leading to skeletal ...
Valeria Novelli +8 more
doaj +1 more source
Influence of mental stress on the pulse wave features of photoplethysmograms
Mental stress is a major burden for our society. Invasive and non-invasive methods have been proposed to monitor and quantify it using various sensors on and off body.
Patrick Celka +6 more
doaj +1 more source
Investigation of a Q fever outbreak in a Scottish co-located slaughterhouse and cutting plant [PDF]
Outbreaks of Q fever are rare in the UK. In 2006, the largest outbreak of Q fever in Scotland occurred at a co-located slaughterhouse and cutting plant with 110 cases.
Australian Government +21 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Soil moisture controls on patterns of grass green-up in Inner Mongolia: an index based approach [PDF]
Water availability is one of the most important environmental controls on vegetation phenology, especially in semi-arid regions. It is often represented in terms of soil moisture in small-scale studies, whereas it tends to be represented by precipitation
H. Liu +4 more
doaj +1 more source
Electronic superlattice revealed by resonant scattering from random impurities in Sr3Ru2O7 [PDF]
Resonant elastic x-ray scattering (REXS) is an exquisite element-sensitive tool for the study of subtle charge, orbital, and spin superlattice orders driven by the valence electrons, which therefore escape detection in conventional x-ray diffraction (XRD)
Bohnenbuck, B. +18 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Movement scientists have proposed to ground the relation between prosody and gesture in ‘vocal-entangled gestures’, defined as biomechanical linkages between upper limb movement and the respiratory–vocal system. Focusing on spoken language negation, this
Simon Harrison
doaj +1 more source
An 'Importance' Map of Signs and Symptoms to Classify Diabetic Polyneuropathy: An Exploratory Data Analysis. [PDF]
Early diagnosis of diabetic polyneuropathy (DPN) is critical for a good prognosis. We aimed to identify different groups of patients, based on the various common clinical signs and symptoms of DPN, that represent a progressive worsening of the disease ...
Isabel C N Sacco +3 more
doaj +1 more source

