Prevalence and Incidence of Treatment-Range Adolescent Idiopathic Scoliosis Diagnosed in Ontario Between 2012 and 2021: Validating a Population-Based Health Administrative Algorithm for Case Identification in Youth Aged 10-17 Years. [PDF]
Dermott JA +5 more
europepmc +1 more source
Durum Wheat cv. Svevo Reference Genome Rel.2.0: A Comprehensive Tool for Wheat Genomics
ABSTRACT Advancements in plant genome sequencing and assembly have enabled the production of increasingly accurate and contiguous genome sequences. Here, we present the chromosome‐level assembly of the durum wheat (Triticum turgidum L. ssp. durum, cv. Svevo) reference genome produced using accurate long‐reads, optical mapping and Hi‐C. The new assembly
Elisabetta Mazzucotelli +71 more
wiley +1 more source
Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer. [PDF]
Lautert-Dutra W +13 more
europepmc +1 more source
Neonatal Adverse Outcomes in Métis Children in Alberta, Canada: A Retrospective Cohort Study
ABSTRACT Background Composite indicators of neonatal morbidity specific to Métis populations in Canada are lacking. Objectives To estimate the incidence of neonatal morbidity and neonatal death among Métis neonates in Alberta, and to identify maternal and neonatal factors associated with neonatal morbidity. Methods Population‐based retrospective cohort
Jesus Serrano‐Lomelin +13 more
wiley +1 more source
Health services use for injury amongst persons experiencing homelessness in Ontario, Canada: a population-based retrospective matched cohort study. [PDF]
Visser C +4 more
europepmc +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
Drivers to Stay or to Leave: Perceptions of the Nursing Work Environment Across Diverse Healthcare Sectors. [PDF]
M Connelly D +3 more
europepmc +1 more source

