Results 131 to 140 of about 13,737 (221)

Durum Wheat cv. Svevo Reference Genome Rel.2.0: A Comprehensive Tool for Wheat Genomics

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Advancements in plant genome sequencing and assembly have enabled the production of increasingly accurate and contiguous genome sequences. Here, we present the chromosome‐level assembly of the durum wheat (Triticum turgidum L. ssp. durum, cv. Svevo) reference genome produced using accurate long‐reads, optical mapping and Hi‐C. The new assembly
Elisabetta Mazzucotelli   +71 more
wiley   +1 more source

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer. [PDF]

open access: yesProstate
Lautert-Dutra W   +13 more
europepmc   +1 more source

Neonatal Adverse Outcomes in Métis Children in Alberta, Canada: A Retrospective Cohort Study

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Composite indicators of neonatal morbidity specific to Métis populations in Canada are lacking. Objectives To estimate the incidence of neonatal morbidity and neonatal death among Métis neonates in Alberta, and to identify maternal and neonatal factors associated with neonatal morbidity. Methods Population‐based retrospective cohort
Jesus Serrano‐Lomelin   +13 more
wiley   +1 more source

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski   +3 more
wiley   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu   +5 more
wiley   +1 more source

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