Results 221 to 230 of about 223,364 (391)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Does intraspecific variation in juvenile Late Cretaceous ammonoids correlate with their systematic position, longevity and paleogeography? [PDF]

Swiss J Palaeontol
Tajika A, Iida T, Wani R, Landman NH, Ikuno K, Klug C.   +5 more
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Perianth symmetry in sexually differentiated flowers of <i>Akebia quinata</i> (Lardizabalaceae). [PDF]

PeerJ
Neustupa J, Woodard K.
europepmc   +1 more source

The Ontogeny of Sugar Transport in Kidney [PDF]

, 1978
Karl S. Roth, Shing Mei Hwang, Marc Yudkoff, Stanton Segal   +3 more
openalex   +1 more source

T cell development in the chicken [PDF]

, 1994
Bernot, Bucy, Bucy, C.H. CHEN, Chan, Char, Chen, Chen, Chen, Chen, Chen, Cihak, Cihak, Cihak, Coltey, Coltey, Cooper, Davidson, Dunon, George, Göbel, Haas, Kasahara, Lahti, M.D. COOPER, McCormack, Quere, Schiffer, Sowder, T. KUBOTA, T.W.F. GÖBEL, Tjoelker, Veillette, Wyss-Coray   +33 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Diversification of the stem vascular system in a clade of recent radiation and multiple habit transitions: The Bunchosia clade (Malpighiaceae). [PDF]

Am J Bot
Quintanar-Castillo A, Amorim AM, Pace MR.   +2 more
europepmc   +1 more source

Ontogeny of the Vegetative and the Reproductive Apices in Pharbitis nil Chois. I.

, 1965
Yasuko Marushige
openalex   +2 more sources

Social olfaction: a review of the ontogeny of olfactory influences on vertebrate behavior [PDF]

, 1975
MaryLou Cheal
openalex   +1 more source