Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Behavioral algorithms of ontogenetic switching in larval and juvenile zebrafish phototaxis. [PDF]
Capelle MQ +3 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Ammonia Exposure Elevated 5-HT Expression, Reprogrammed Transcriptome and Microbiota Community in Yellow Catfish (<i>Pelteobagrus fulvidraco</i>) Gill During Early Ontogeny. [PDF]
Jian Y +8 more
europepmc +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Photosynthetic activity in the heterotrophic plant genus Cuscuta (Convolvulaceae) is modulated by phylogeny and ontogeny. [PDF]
Schneider AC +5 more
europepmc +1 more source
Co-variation and trade-offs in ontogenetic scaling of growth and metabolic rates in teleost fish. [PDF]
Rosén A +8 more
europepmc +1 more source
Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity. [PDF]
Baber RW +8 more
europepmc +1 more source
Influence of temperature on developmental and biochemical traits of the red squat lobster <i>Grimothea monodon</i> (H. Milne Edwards, 1837) during early ontogeny. [PDF]
Quispe-Machaca M +3 more
europepmc +1 more source

