Results 281 to 290 of about 223,364 (391)

Comments on the ontogeny of Typhlonectes obesus, particularly its dentition and feeding

, 1978
Marvalee H. Wake
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Gestational age and fetal hypothyroidism Alter the porcine thyroid and local hepatic and renal renin-angiotensin systems. [PDF]

Physiol Rep
Smith AA, Pasternak JA.
europepmc   +1 more source

ONTOGENY OF SUPPRESSOR CELLS II. SUPPRESSION OF GRAFT-VERSUS-HOST AND MIXED LEUKOCYTE CULTURE RESPONSES BY EMBRYONIC CELLS

, 1978
Amiela Globerson, Tehila Umiel
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

A CSF-cytokine code predicts macrophage response polarity and tumor outcomes

Vallelian F, Schaer D, Schulthess-Lutz N, Peterhans M, Baselgia L, Eschment M, Humar R.   +6 more
europepmc   +1 more source

<i>Massospondylus</i> embryos and hatchling provide new insights into early sauropodomorph ontogeny. [PDF]

Swiss J Palaeontol
Mooney ED, Maho T, Rowe DCT, Scott D, Reisz RR.   +4 more
europepmc   +1 more source

Ontogeny of lymphocyte subpopulations in human fetal liver.

, 1976
Sudhir Gupta, R. Pahwa, R J O'Reilly, Robert A. Good, Frederick P. Siegal   +4 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

A model of early-life interactions between the gut microbiome and adaptive immunity provides insights into the ontogeny of immune tolerance. [PDF]

PLoS Biol
Tepekule B, Lim AI, Metcalf CJE.
europepmc   +1 more source