Results 161 to 170 of about 147,101 (317)
Benchmarking multiple gene ontology enrichment tools reveals high biological significance, ranking, and stringency heterogeneity among datasets. [PDF]
de Oliveira FHS, Gomes FA, Feltes BC.
europepmc +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Assessing the effectiveness of ontology-grounded AI term extraction using OntoGPT for environmental evidence synthesis. [PDF]
Hodgson RY +8 more
europepmc +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Advancing the bioassay ontology through integrated PK/PD and safety pharmacology representation. [PDF]
Glenny-Pescov J +7 more
europepmc +1 more source
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He +17 more
wiley +1 more source
SergeakaAimate/Ontology-Lab: Human in a Duck Suit: x ∈ A ⇔ P(x) = P(A)
Serge Magomet aka Aimate
openalex +1 more source
The Ontological Origin of Agamben’s Political Philosophy - An Interpretation of quodlibet ens -
Dong Wook Seo
openalex +2 more sources

