Results 201 to 210 of about 275,690 (365)

System Ontology and Descriptionism - Bertalanffy's View and New Developments

, 1970
Klaus Kornwachs
openalex   +2 more sources

On moving on on ontologies [PDF]

, 1994
Robin P. Fawcett
openalex   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

Advanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu, Yuanyuan Zhu, Guangjue Tang, Ming Shan, Puwen Tan, Ying Yi, Xiyuan Zhang, Man Liu, Xinyu Li, Le Wu, Jia Chen, Hailong Zheng, Yan Huang, Zhuan Li, Xiaobo Li, Dong Wang   +15 more
wiley   +1 more source

A Python toolkit for dealing with Petri nets over ontological graphs [PDF]

arXiv
We present theoretical rudiments of Petri nets over ontological graphs as well as the designed and implemented Python toolkit for dealing with such nets. In Petri nets over ontological graphs, the domain knowledge is enclosed in a form of ontologies. In this way, some valuable knowledge (especially in terms of semantic relations) can be added to model ...
arxiv  

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

Bottom-up construction of ontologies [PDF]

, 1998
P.E. van der Vet, Nicolaas Mars
openalex   +1 more source

Integrating Spatial and Single‐Nucleus Transcriptomic Data to Assess the Effects of Intrauterine Hyperglycemia on Fetal Pancreatic Development

Advanced Science, EarlyView.
Maternal pregestational diabetes mellitus (PGDM) induced metabolic stress in fetal mice pancreas, alongside significantly decreased insulin secretion, altered cell‐cell communication, and distinct changes in cellular niches. Abstract Maternal pregestational diabetes mellitus (PGDM) can lead to adverse fetal outcomes, including lasting impacts on ...
Yu Deng, Shuting Wan, Zan Yuan, Huixia Yang   +3 more
wiley   +1 more source

To Be or Not To Be: Vector ontologies as a truly formal ontological framework [PDF]

arXiv
Since Edmund Husserl coined the term "Formal Ontologies" in the early 20th century, a field that identifies itself with this particular branch of sciences has gained increasing attention. Many authors, and even Husserl himself have developed what they claim to be formal ontologies.
arxiv  

INTRODUCTION TO THE DILEMMAS OF SOCIAL REALITY—ONTOLOGICAL

, 1979
Piotr Sztompka
openalex   +1 more source

Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Advanced Science, EarlyView.
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan, Xing He, Su Wu, Na Xiong, Xinyu Hou, Heting Wang, Diane Somlo, Martin Spiess, Haiyang Wang, Jifeng Yang, Chunliang Li, Shasha Li, Wenbin Ma, Yanming Chen, Jun Cui, Ling Qi, Guojun Shi   +16 more
wiley   +1 more source