Results 71 to 80 of about 275,690 (365)

Quality assurance and enrichment of biological and biomedical ontologies and terminologies

BMC Medical Informatics and Decision Making, 2020
Biological and biomedical ontologies and terminologies are used to organize and store various domain-specific knowledge to provide standardization of terminology usage and to improve interoperability.
Ankur Agrawal, Licong Cui
doaj   +1 more source

From the measurement problem to the primitive ontology programme [PDF]

, 2019
The paper retraces the development from the measurement problem to the primitive ontology programme. It assesses the contribution of the GRW theory to this programme and discusses the pros and cons of the GRWm matter density ontology and the GRWf flash ontology in comparison to the Bohmian particle ontology.
arxiv   +1 more source

Desiderata for an ontology of diseases for the annotation of biological datasets. [PDF]

, 2009
There is a plethora of disease ontologies available, all potentially useful for the annotation of biological datasets. We define seven desirable features for such ontologies and examine whether or not these features are supported by eleven disease ...
Anita Burgun, Olivier Bodenreider
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

OnEX: Exploring changes in life science ontologies

BMC Bioinformatics, 2009
Background Numerous ontologies have recently been developed in life sciences to support a consistent annotation of biological objects, such as genes or proteins.
Gross Anika, Kirsten Toralf, Hartung Michael, Rahm Erhard   +3 more
doaj   +1 more source

Ontology (Science) [PDF]

, 2008
Increasingly, in data-intensive areas of the life sciences, experimental results are being described in algorithmically useful ways with the help of ontologies.
Barry Smith
core   +2 more sources

An Ontological Approach to Representing the Product Life Cycle [PDF]

, 2019
The ability to access and share data is key to optimizing and streamlining any industrial production process. Unfortunately, the manufacturing industry is stymied by a lack of interoperability among the systems by which data are produced and managed, and
Ali, Munira Mohd, Kiritsi, Dimitris, Otte, J. Neil, Rai, Rahul, Rudnicki, Ron, Smith, Barry, Yang, Ruoyu, Zhang, Binbin   +7 more
core   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

A platform for semantic web studies [PDF]

, 2010
The Semantic Web can be seen as a large, heterogeneous network of ontologies and semantic documents. Characterizing these ontologies, the way they relate and the way they are organized can help in better understanding how knowledge is produced and ...
Allocca, Carlo, d'Aquin, Mathieu, Motta, Enrico   +2 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source