Results 21 to 30 of about 601,327 (249)

Querying clinical data in HL7 RIM based relational model with morph-RDB

Journal of Biomedical Semantics, 2017
Background Semantic interoperability is essential when carrying out post-genomic clinical trials where several institutions collaborate, since researchers and developers need to have an integrated view and access to heterogeneous data sources.
Freddy Priyatna, Raul Alonso-Calvo, Sergio Paraiso-Medina, Oscar Corcho   +3 more
doaj   +1 more source

Preserving conceptual model semantics in the forward engineering of relational schemas

Frontiers in Computer Science, 2022
Forward engineering relational schemas based on conceptual models (in languages such as UML and ER) is an established practice, with several automated transformation approaches discussed in the literature and implemented in production tools.
Gustavo L. Guidoni, Gustavo L. Guidoni, João Paulo A. Almeida, Giancarlo Guizzardi   +3 more
doaj   +1 more source

DTAG: A Methodology for Aggregating Digital Twins Using the WoTDT Ontology

Applied Sciences
The advancement of digital twins (DTws) has been instrumental in various scientific and industrial domains, facilitating real-time monitoring, analysis, and optimisation of complex systems.
Salvador González-Gerpe, María Poveda-Villalón, Raúl García-Castro   +2 more
doaj   +1 more source

Entanglement—A Higher Order Symmetry

Physical Sciences Forum, 2023
Can we accurately model the spin state of a quantum particle? If so, we should be able to make identical copies of such a state and also obtain its mirror image.
Paul O’Hara
doaj   +1 more source

bio-ontology-research-group/deepgo: Function prediction using a deep ontology-aware classifier

, 2016
Function prediction using a deep ontology-aware ...
Kulmanov, Maxat, Hoehndorf, Robert
core   +1 more source

A note on ontology localization [PDF]

, 2010
Cimiano P, Montiel-Ponsoda E, Buitelaar P, Espinoza M, Gomez-Perez A. A note on ontology localization. Journal of Applied Ontology (JAO).
Gomez-Perez, Asuncion, Espinoza, Mauricio, Montiel-Ponsoda, Elena, Buitelaar, Paul, Cimiano, Philipp ; https://orcid.org/   +4 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

INCATools/ontology-access-kit: v0.1.8

, 2022
What's Changed Taxon constraints; multi-ontology arguments by @cmungall in https://github.com/INCATools/ontology-access-kit/pull/19 taxon constraints by @cmungall in https://github.com/INCATools/ontology-access-kit/pull/20 mappings by @cmungall in https:
marcin p. joachimiak, Chris Mungall, Harshad, marcin pawel joachimiak, Patrick Kalita, Sujay Patil, marcin joachimiak, Charles Tapley Hoyt, Nico Matentzoglu, Harry Caufield   +9 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Combining lexical and context features for automatic ontology extension.

, 2018
BACKGROUND:Ontologies are widely used across biology and biomedicine for the annotation of databases. Ontology development is often a manual, time-consuming, and expensive process.
Kafkas, Senay, Althubaiti, Sara, Abdelhakim, Marwa, Hoehndorf, Robert   +3 more
core   +1 more source