Results 31 to 40 of about 910,309 (299)

Representation Phase: Ontology Usage Ontology (U Ontology)

open access: yes, 2018
The huge increase in the use of ontologies and Semantic Web data has increased the need for usage-related information to assist stakeholders (or users) to make effective use of currently available semantic information. As noted in earlier chapters, stakeholders can be different groups of users such as ontology developers, domain experts, application ...
Ashraf, J   +3 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Entanglement—A Higher Order Symmetry

open access: yesPhysical Sciences Forum, 2023
Can we accurately model the spin state of a quantum particle? If so, we should be able to make identical copies of such a state and also obtain its mirror image.
Paul O’Hara
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Interpreting Literary Characters Through Diagnostic Properties

open access: yesHumanities
This paper investigates an approach to studying analytic relations (identity, similarity, borrowing, etc.) between literary characters using properties and, in particular, properties that are interpretively considered as diagnostic.
Emilio M. Sanfilippo   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Querying clinical data in HL7 RIM based relational model with morph-RDB

open access: yesJournal of Biomedical Semantics, 2017
Background Semantic interoperability is essential when carrying out post-genomic clinical trials where several institutions collaborate, since researchers and developers need to have an integrated view and access to heterogeneous data sources.
Freddy Priyatna   +3 more
doaj   +1 more source

Ontology Matching

open access: yes, 2007
No abstract available.
Euzenat, Jérôme, Shvaiko, Pavel
openaire   +5 more sources

Foundational ontologies meet ontology matching: A survey

open access: yesSemantic Web, 2022
Ontology matching is a research area aimed at finding ways to make different ontologies interoperable. Solutions to the problem have been proposed from different disciplines, including databases, natural language processing, and machine learning. The role of foundational ontologies for ontology matching is an important one, as they provide a well ...
Trojahn, Cassia   +4 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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