Results 81 to 90 of about 583,139 (291)

No-signaling in topos formulation and a common ontological basis for classical and non-classical physical theories

open access: yesZagadnienia Filozoficzne w Nauce, 2020
Starting from logical structures of classical and quantum mechanics we reconstruct the logic of so-called no-signaling theories, where the correlations among subsystems of a composite system are restricted only by a simplest form of causality forbidding ...
Marek Kuś
doaj  

Performing ontology

open access: yesSocial Studies of Science, 2014
Ontology, and in particular, the so-called ontological turn, is the topic of a recent themed issue of Social Studies of Science (Volume 43, Issue 3, 2013). Ontology, or metaphysics, is in philosophy concerned with what there is, how it is, and forms of being.
openaire   +4 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Analogicity in Computer Science. Methodological Analysis

open access: yesStudies in Logic, Grammar and Rhetoric, 2020
Analogicity in computer science is understood in two, not mutually exclusive ways: 1) with regard to the continuity feature (of data or computations), 2) with regard to the analogousness feature (i.e.
Stacewicz Paweł
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Ontology localization

open access: yesProceedings of the fifth international conference on Knowledge capture, 2009
nternational organizations (e.g., FAO1 , WHO2 , etc.) are increasingly expressing the need for multilingual ontologies for di®erent purposes, e.g., ontology-based multilingual machine translation, multilingual informa- tion retrieval. However, most of the ontologies built so far have mainly English or another natural language as basis.
Espinoza Mejía, Mauricio   +2 more
openaire   +3 more sources

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Changing Ontology Breaks the Queries

open access: yes, 2006
Updating an ontology that is in use may result in inconsistencies between the ontology and the knowledge base, dependent ontologies and applications/services.
Liang, Yaozhong   +2 more
core   +1 more source

Evaluating Ontology Modules Using an Entropy Inspired Metric

open access: yes, 2008
The focus of ontology modularization to date has largely been on the creation of techniques to carry out ontology modularization. This creates a problem in evaluating the results of the different techniques.
Iannone, Luigi   +4 more
core   +2 more sources

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