Results 61 to 70 of about 601,327 (249)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Ontology Change Management in Protégé
, 2005 Ontology schemas tend to change and evolve over time to meet new requirements. This change may invalidate dependent applications if there is no dynamic adaptation to the changes made to underlying ontologies.
Liang, Yaozhong +2 more
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Building an Advance Domain Ontology Model of Information Science (OIS) [PDF]
, 2014 The paper describes the process of modelling domain knowledge of Information Science (IS) by creating an Ontology of Information Science domain (OIS).
Lu, Joan, Sawsaa, Ahlam
core +3 more sources
Zagadnienia Filozoficzne w Nauce, 2020 Starting from logical structures of classical and quantum mechanics we reconstruct the logic of so-called no-signaling theories, where the correlations among subsystems of a composite system are restricted only by a simplest form of causality forbidding ...
Marek Kuś
doaj
Analogicity in Computer Science. Methodological Analysis
Studies in Logic, Grammar and Rhetoric, 2020 Analogicity in computer science is understood in two, not mutually exclusive ways: 1) with regard to the continuity feature (of data or computations), 2) with regard to the analogousness feature (i.e.
Stacewicz Paweł
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Ontology Winnowing: A Case Study on the AKT Reference Ontology
, 2005 Many ontologies are built for the main purpose of representing a domain, rather than to meet the requirements of a specific application. When applications and services are deployed over an ontology, it is sometimes the case that only few parts of the ...
Harris, Steven +2 more
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