Results 201 to 210 of about 42,984 (264)

Next generation biobanking ontology: introducing-omics contextual data to biobanking ontology. [PDF]

Bioinform Adv
Alghamdi D, Dooley DM, Samman M, AlFaiz A, Hsiao WWL.   +4 more
europepmc   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Personally speaking: Developing and evaluating an ontology of dimensions of meaning for self-disclosure with a conversational assistant. [PDF]

PLoS One
Ferland L, Qu H, Koutstaal W.
europepmc   +1 more source

A review of the state of the art in Machine Learning on the Semantic Web: Technical Report CSTR-05-003 [PDF]

, 2004
Price, S
core  

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source

Structured clinical approach to enable large language models to be used for improved clinical diagnosis and explainable reasoning. [PDF]

Commun Med (Lond)
Ayoub M, Zhao H, Li L, Yang D, Hussain S, Wahid JA.   +5 more
europepmc   +1 more source

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

Advanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi, Huiquan Shan, Haoping Wang, Xi Guo, Houcheng Li, Bo Han, Senlin Zhu, Fei Wang, Guanghui Tan, Zhannur Niyazbekova, Jilong Ren, Yaqi Zhou, Qi Zhang, Weijie Zheng, Minghui Jia, Ao Zhang, Xuesha Cao, Huizeng Sun, Dongxiao Sun, Lingzhao Fang, Yi Zheng, Xihong Wang, Yu Jiang   +22 more
wiley   +1 more source

A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution. [PDF]

Mamm Genome
Ehlich H, Blease A, Biju R, Gustems M, Song F, Fessele S, Massimi M, Bozonelos K, Ntafis V, Hiltunen AE, Marschall S, Stoeger C, Khorshidi Z, Ziadi A, Jambou K, Armagno A, Scavizzi F, Raspa M, Fernandez J, Del Hierro MJ, Ayadi A, Pensavalle J, Prevost G, Dufková L, Krupkova M, Nickl P, Krimpenfort P, van de Ven M, Jonkers J, Valera Vázquez G, Raess M, Beckers J, Moles A, Dahlhoff M, Montoliu L, Hérault Y, Hinttala R, Kontoyiannis DL, Sedlacek R, Hrabě de Angelis M, Boersma AA, Matteoni R.   +41 more
europepmc   +1 more source

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Unlocking the power of groups in youth sport: a proof-of-concept evaluation of the Together For Us (T4Us) intervention. [PDF]

Pilot Feasibility Stud
Bruner MW, McLaren CD, Schertzinger M, Boardley ID, Martin LJ, Slatcher RB, Vella S, Carré JM, Fransen K.   +8 more
europepmc   +1 more source