Results 231 to 240 of about 42,984 (264)

Towards a standard benchmark for phenotype-driven variant and gene prioritisation algorithms: PhEval - Phenotypic inference Evaluation framework. [PDF]

BMC Bioinformatics
Bridges Y, Souza V, Cortes KG, Haendel M, Harris NL, Korn DR, Marinakis NM, Matentzoglu N, McLaughlin JA, Mungall CJ, Odell A, Osumi-Sutherland D, Robinson PN, Smedley D, Jacobsen JOB.   +14 more
europepmc   +1 more source

Targeting the Mapk13‐Tcf1‐Slc7a5 Axis via One‐Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy

Advanced Science, EarlyView.
This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi, Di Wu, Jing Liu, Shi Chen, Liu Song, Bin Xie, Aini Xie, Peixiang Lan, Zhishui Chen   +8 more
wiley   +1 more source

P.O.L.A.R. Star: A New Framework Developed and Applied by One Mid-Sized Pharmaceutical Company to Drive Digital Transformation in R&D. [PDF]

Pharmaceut Med
Mariani R, De Vuono MC, Businaro E, Ivaldi S, Dell'Armi T, Gallo M, Ardigò D.   +6 more
europepmc   +1 more source

MCPmed: a call for Model Context Protocol-enabled bioinformatics web services for LLM-driven discovery. [PDF]

Brief Bioinform
Flotho M, Diks IF, Flotho P, Molano LG, Hirsch P, Keller A.   +5 more
europepmc   +1 more source

An unsupervised XAI framework for dementia detection with context enrichment. [PDF]

Sci Rep
Singh D, Brima Y, Levin F, Becker M, Hiller B, Hermann A, Villar-Munoz I, Beichert L, Bernhardt A, Buerger K, Butryn M, Dechent P, Düzel E, Ewers M, Fliessbach K, Freiesleben SD, Glanz W, Hetzer S, Janowitz D, Görß D, Kilimann I, Kimmich O, Laske C, Levin J, Lohse A, Luesebrink F, Munk M, Perneczky R, Peters O, Preis L, Priller J, Prudlo J, Prychynenko D, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schneider A, Droste Zu Senden L, Schott BH, Spottke A, Synofzik M, Wiltfang J, Jessen F, Weber MA, Teipel SJ, Dyrba M.   +46 more
europepmc   +1 more source

Advancing real-world evidence in Brazil: regulatory gaps and global lessons. [PDF]

Lancet Reg Health Am
Cézar de Aquino N, Reichert CO, Alberto de Padua Covas Lage L, Culler HF, Rosa Roitberg FS, Rocha V, Rocha Alves FN, Pereira J.   +7 more
europepmc   +1 more source

Population health management through human phenotype ontology with policy for ecosystem improvement. [PDF]

Front Artif Intell
Henry JA.
europepmc   +1 more source

Exploiting the UMLS Metathesaurus in the Ontology Alignment Evaluation Initiative

, 2016
Jimenez−Ruiz, E, Grau, B, Horrocks, I
openaire   +1 more source

Lessons Learned From European Health Data Projects With Cancer Use Cases: Implementation of Health Standards and Internet of Things Semantic Interoperability.

J Med Internet Res
Gyrard A, Abedian S, Gribbon P, Manias G, van Nuland R, Zatloukal K, Nicolae IE, Danciu G, Nechifor S, Marti-Bonmati L, Mallol P, Dalmiani S, Autexier S, Jendrossek M, Avramidis I, Garcia Alvarez E, Holub P, Blanquer I, Boden A, Hussein R.   +19 more
europepmc   +1 more source

First results of the ontology alignment evaluation initiative 2006

, 2016
openaire   +1 more source