Results 31 to 40 of about 283,563 (261)

Developing a Novel Ontology for Cybersecurity in Internet of Medical Things-Enabled Remote Patient Monitoring

Sensors
IoT has seen remarkable growth, particularly in healthcare, leading to the rise of IoMT. IoMT integrates medical devices for real-time data analysis and transmission but faces challenges in data security and interoperability.
Kulsoom S. Bughio, David M. Cook, Syed Afaq A. Shah   +2 more
doaj   +1 more source

DOMAIN ONTOLOGY DEVELOPMENT FRAMEWORK: THE THESAURUS, REFERENCE SOURCE, KNOWLEDGE ENGINEER AND DOMAIN EXPERT APPROACH

Asia-Pacific Journal of Information Technology and Multimedia, 2014
There were a variety of difficulties that users have to face in searching for information through Internet. Past research had shown that users faced the problem of using vocabulary in searching for information through the web.
Siti Farhana Mohamad Hashim, Juhana Salim, Shahrul Azman Mohd. Noah   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Ontology-based data framework for the digital preservation cultural heritage: A case of Subak

Matrix: Jurnal Manajemen Teknologi dan Informatika
Cultural heritage is increasingly fading due to the influence of globalization and social changes that shift traditional values. Digitalization is critical to addressing the degradation of cultural heritage knowledge by enabling more accessible storage ...
Ni Kadek Dessy Hariyanti, Linawati, I Made Oka Widyantara   +2 more
doaj   +1 more source

Toward a systematic conflict resolution framework for ontologies

Journal of Biomedical Semantics, 2021
Background The ontology authoring step in ontology development involves having to make choices about what subject domain knowledge to include. This may concern sorting out ontological differences and making choices between conflicting axioms due to ...
C. Maria Keet, Rolf Grütter
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Activities of Daily Living Ontology for Ubiquitous Systems: Development and Evaluation

Sensors, 2018
Ubiquitous eHealth systems based on sensor technologies are seen as key enablers in the effort to reduce the financial impact of an ageing society. At the heart of such systems sit activity recognition algorithms, which need sensor data to reason over ...
Przemysław R. Woznowski, Emma L. Tonkin, Peter A. Flach   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Using Large Language Models for Ontology Development

Engineering Proceedings
This paper explores the application of Large Language Models (LLMs) for ontology development, focusing specifically on cloud service ontologies. We demonstrate how LLMs can streamline the ontology development process by following a modified Ontology ...
Darko Andročec
doaj   +1 more source