Results 61 to 70 of about 283,563 (261)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Intercropping in Rubber Plantation Ontology for a Decision Support System

Journal of Information Science Theory and Practice, 2019
Planting intercropping in rubber plantations is another alternative for generating more income for farmers. However, farmers still lack the knowledge of choosing plants.
Phoksawat, Kornkanok, Mahmuddin, Massudi, Ta'a, Azman   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Representing kidney development using the gene ontology. [PDF]

PLoS ONE, 2014
Gene Ontology (GO) provides dynamic controlled vocabularies to aid in the description of the functional biological attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org).
Yasmin Alam-Faruque, David P Hill, Emily C Dimmer, Midori A Harris, Rebecca E Foulger, Susan Tweedie, Helen Attrill, Douglas G Howe, Stephen Randall Thomas, Duncan Davidson, Adrian S Woolf, Judith A Blake, Christopher J Mungall, Claire O'Donovan, Rolf Apweiler, Rachael P Huntley   +15 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Formalisation of the sofware component ontology specification

Lietuvos Matematikos Rinkinys, 2005
This paper is devoted to the development and specification problems of software component ontology. The formalisation of the proposed component ontology is presented, too. The choice of ontology interpretation  is motivated.
Lina Bagušytė, Audronė Lupeikienė
doaj   +3 more sources

Application of an Improved Formal Model of the Hybrid Development of Ontologies in Complex Information Systems

Applied Sciences, 2020
Ontologies in artificial intelligence systems are an effective way to represent and integrate knowledge and data. The property of such structures is that any subject area is accurately described in formal language.
Yousef Ibrahim Daradkeh, Iryna Tvoroshenko   +1 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

CO-OPERATIVE ONTOLOGY DEVELOPMENT APPROACH [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2013
The paper deals with an approach to co-operative ontology development based on the ideology of version control systems with a central repository. Some problem solutions of ontology backward compatibility and resolution of conflicts between updates made ...
A. V. Nevidimov, I. A. Bessmertny
doaj