Results 131 to 140 of about 1,174,184 (329)

Opening the Black Box of Ontology Matching [PDF]

open access: yes, 2013
Due to the high heterogeneity of ontologies, a combination of many methods is necessary in order to discover correctly the semantic correspondences between their elements. An ontology matching tool can be seen as a collection of several matching components, each implementing a specific method dealing with a specific heterogeneity type (terminological ...
Ngo, Duy Hoa   +2 more
openaire   +5 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution

open access: yesJournal of Biomedical Semantics, 2011
Background Ontologies are increasingly used to structure and semantically describe entities of domains, such as genes and proteins in life sciences. Their increasing size and the high frequency of updates resulting in a large set of ontology versions ...
Kirsten Toralf   +3 more
doaj   +1 more source

Full-text Support for Publish/Subscribe Ontology Systems [PDF]

open access: yesarXiv, 2013
We envision a publish/subscribe ontology system that is able to index millions of user subscriptions and filter them against ontology data that arrive in a streaming fashion. In this work, we propose a SPARQL extension appropriate for a publish/subscribe setting; our extension builds on the natural semantic graph matching of the language and supports ...
arxiv  

The Information-Flow Approach to Ontology-Based Semantic Integration

open access: yes, 2010
In this article we argue for the lack of formal foundations for ontology-based semantic alignment. We analyse and formalise the basic notions of semantic matching and alignment and we situate them in the context of ontology-based alignment in open-ended ...
Kalfoglou, Yannis, Schorlemmer, Marco
core  

Towards the ontology-based approach for factual information matching [PDF]

open access: yes, 2018
Factual information is information based on facts or relating to facts. The reliability of automatically extracted facts is the main problem of processing factual information.
Cherednichenko, Olga   +2 more
core  

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng   +11 more
wiley   +1 more source

Automatizing the Evaluation of Model Matching Systems [PDF]

open access: yes, 2010
International audienceModel-Driven Engineering (MDE) and the Semantic Web are valuable paradigms. This paper sketches how to use a scientific and technical result around MDE in the Semantic Web.
Garcés, Kelly   +2 more
core   +4 more sources

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

open access: yesAdvanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu   +15 more
wiley   +1 more source

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