Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa+2 more
wiley +1 more source
Myosin VI is expressed in developing ovarian follicles in <i>Drosophila</i> but is not essential for effective oogenesis. [PDF]
Lenartowski R+8 more
europepmc +1 more source
Benchmarks defining high‐quality sperm in the common marmoset (Callithrix jacchus)
Abstract Background Common marmosets (Callithrix jacchus) are increasingly recognized as valuable nonhuman primates (NHPs) for biomedical research due to their small size and short reproductive cycle and lifespan relative to other NHP species. Maximizing the utility of captive research marmosets, including genetically manipulated animals, will require ...
Niloofar Sadeghi+4 more
wiley +1 more source
<i>DLGAP5</i> mutations Disrupt Normal Chromosome Segregation and Spindle Formation of human Oocyte Meiosis and Lead to Female Infertility. [PDF]
Wang M+8 more
europepmc +1 more source
Abstract Background Sperm DNA damage is associated with reduced male fertility after natural conception and intrauterine insemination. However, the impact on in vitro fertilization (IVF) and especially intracytoplasmic sperm injection (ICSI) treatments is still unclear.
Preben Christensen+6 more
wiley +1 more source
Extracellular vesicles in reproductive biology and disorders: a comprehensive review. [PDF]
Wang J+8 more
europepmc +1 more source
Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction
Abstract Background Sperm cryopreservation is a consolidate option for long‐term male fertility preservation. The freezing/thawing procedure causes detrimental effects to spermatozoa, including damage to viability, motility, membrane composition, and DNA, whereas the effect on sperm chromatin compaction is less studied.
Lara Tamburrino+8 more
wiley +1 more source
Comparing Dydrogesterone Versus Medroxyprogesterone in Progestin-Primed Ovarian Stimulation (PPOS) for Patients Undergoing In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Systematic Review. [PDF]
Muharam R+7 more
europepmc +1 more source
Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice
Abstract Background Inhibition of sperm maturation in the epididymis is a promising post‐testicular strategy for short‐acting male contraceptives. It has been shown that ROS1, a receptor tyrosine kinase expressed in the epididymis, is essential for epididymal differentiation, sperm maturation, and male fertility in mice.
Yuki Oyama+9 more
wiley +1 more source
Role of ZBED3 in PALD1/PIP2- dependent calcium homeostasis during oocyte maturation. [PDF]
Ni D+8 more
europepmc +1 more source