Results 31 to 40 of about 5,426 (249)

Obstetric outcome in donor oocyte pregnancies: a matched-pair analysis

open access: yesReproductive Biology and Endocrinology, 2012
Background To investigate the obstetrical and perinatal impact of oocyte donation, a cohort of women who conceived after OD was compared with a matched control group of women who became pregnant through in vitro fertilisation with autologous oocytes (AO).
Stoop Dominic   +7 more
doaj   +1 more source

FACTORS AFFECTING THE OUTCOME OF OOCYTE DONATION CYCLES [PDF]

open access: yesActa Medica Iranica, 2005
The success of oocyte donation is influenced by multiple factors. We performed a retrospective analysis to evaluate prognostic factors in oocyte donation cycles.
L. Safdarian, S. Peyvandi
doaj   +2 more sources

Ethical Issues and Controversies in Oocyte Donation and Recipiency: The Oocyte-Sharing Model in China

open access: yesClinical and Experimental Obstetrics & Gynecology
Objective: Oocyte donation combined with in vitro fertilization and embryo transfer (IVF-ET) technology enables women who are unable to obtain or use their own oocytes due to advanced age or various causes of ovarian dysfunction, to ...
Hang Yu, Lifan Peng
doaj   +1 more source

Assisted reproductive technology and hypertensive disorders of pregnancy: systematic review and meta-analyses

open access: yesBMC Pregnancy and Childbirth, 2021
Background Hypertensive disorders of pregnancy (HDP) is one of the most common pregnancy complications and causes of maternal morbidity and mortality. Assisted reproductive technology (ART) has been associated with adverse pregnancy outcomes, including ...
Hui Ju Chih   +3 more
doaj   +1 more source

Comparison of obstetric outcomes of pregnancies after donor-oocyte In vitro fertilization and self-oocyte In vitro fertilization: A retrospective cohort study

open access: yesJournal of Human Reproductive Sciences, 2018
Aims:The aim of this study is to evaluate and compare multiple obstetric and perinatal outcomes between donor-oocyte in vitro fertilization (IVF) and self-oocyte IVF group. Settings and Design: This study was done in a tertiary care center with ART unit.
Vikas Yadav   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Cleavage Stage versus Blastocyst Stage Embryo Transfer in Oocyte Donation Cycles

open access: yesMedicina, 2019
Background and Objective: During the last few years, a trend has been noted towards embryos being transferred at the blastocyst stage, which has been associated with improved rates regarding implantation and clinical pregnancy in comparison to cleavage ...
George Kontopoulos   +10 more
doaj   +1 more source

The Influence of Socio-Cultural Factors on Oocyte Donors' Motivations and Disclosure Decisions

open access: yesChanging Societies & Personalities, 2022
The study focuses on the motivations of Russian oocyte donors and the socio-cultural factors affecting these motivations. We conducted 16 semi-structured interviews with actual or prospective oocyte donors.
Irina G. Polyakova   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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