Results 71 to 80 of about 147,729 (282)

Systematic pathway‐level analysis defines conserved transcriptional divergence between primary lung tumors and cell line models

Animal Models and Experimental Medicine, EarlyView.
Lung cancer cell lines diverge substantially from primary tumors at the transcriptional level. Using single‐sample gene set enrichment analysis and L1‐penalized feature selection across TCGA‐LUAD and CCLE‐LUAD, we identified five Hallmark pathways (E2F targets, G2M checkpoint, IFNγ response, coagulation, and EMT) that discriminated primary tumors from ...
Pritam Bera, Rajesh Raju, Debodipta Das
wiley   +1 more source

Intrafamilial oocyte donation in classic galactosemia: ethical and societal aspects [PDF]

, 2018
Classic galactosemia is a rare inherited disorder of galactose metabolism. Primary ovarian insufficiency (POI) with subfertility affects >80% of female patients and is an important concern for patients and their parents.
M. Haskovic, G. M. W. R. de Wert, Poot, W. J., Rubio-Gozalbo, M. Estela, M. Estela Rubio-Gozalbo, E. Oussoren, Haskovic, M., W. J. Poot, R. J. T. van Golde, van Golde, R. J. T., Krumeich, A., S. H. Benneheij, Benneheij, S. H., Oussoren, E., A. Krumeich, de Wert, G. M. W. R.   +15 more
core   +3 more sources

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

The Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga, Verônica Oliveira‐Bahia, Maria Auxiliadora Ferreira, José Ribamar Felipe Marques, Diva Araújo Guimarães   +4 more
wiley   +1 more source

IVF for premature ovarian failure: first reported births using oocytes donated from a twin sister

Reproductive Biology and Endocrinology, 2010
Background Premature ovarian failure (POF) remains a clinically challenging entity because in vitro fertilisation (IVF) with donor oocytes is currently the only treatment known to be effective.
Sills Eric, Brady Adam C, Omar Ahmed B, Walsh David J, Salma Umme, Walsh Anthony PH   +5 more
doaj   +1 more source

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source

Maternal and fetal outcomes in oocyte donation pregnancies

, 2016
BACKGROUND: Since the first successful use of donated oocytes in 1984, the number of oocyte donation cycles in Europe and the USA has dramatically increased.
I. Cetin, A. Laoreti, L. Mandia, V.M. Savasi   +3 more
core   +1 more source

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

The Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira, Lucas Rezende Penido Paschoal, Fernando José Zara   +2 more
wiley   +1 more source

Psychological factors influencing oocyte donation: A study of Indian donors

Open Health
Infertility is a significant global health issue, particularly in developing nations, where oocyte donation has become crucial for women facing poor oocyte quality.
Lakhote Niharika, Gokani Kairavi H., Vora Priyanka H., Ganla Kedar N., Joshi Manisha   +4 more
doaj   +1 more source

Public opinion regarding oocyte donation in Sweden

, 2003
BACKGROUND: Oocyte donation has been permitted by Swedish legislation since January 2003. According to the law, offspring have the right to receive identifying information about the donor when they reach a mature age.
Skoog Svanberg, A., Lampic, Claudia,, Lampic, C., Bergh, T., Svanberg, A. Skoog, Lundkvist, Ö.   +5 more
core   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source