Stage-dependent DNA damage and mitochondrial dysfunction under simulated microgravity constrain oocyte maturation and are mitigated by melatonin. [PDF]
Cell Commun SignalGao Y +8 more
europepmc +1 more source
Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia
Asia-Pacific Journal of Clinical Oncology, EarlyView.Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski +6 more
wiley +1 more source
Post-Translational Modifications of Tubulin in Oocyte Maturation and Female Infertility. [PDF]
Cytoskeleton (Hoboken)Wang C, Guo R, Wang X, Li H, Zhong T.
europepmc +1 more source
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Editorial: Endocrine regulation of ovarian follicle development and oocyte maturation: molecular mechanisms and functional insights. [PDF]
Front Endocrinol (Lausanne)Pan B, Kodithuwakku SP.
europepmc +1 more source
Andrology, EarlyView.ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro +6 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou +8 more
wiley +1 more source
Correction: The prognostic value of the Oocyte Maturation Index (OMI) on pregnancy outcomes in POSEIDON group 3 and 4 patients: a retrospective cohort study. [PDF]
J Ovarian ResBayram Y +5 more
europepmc +1 more source
Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species
Andrology, EarlyView.ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak +2 more
wiley +1 more source
Improving ARTs: Microfluidics as a Tool for Sperm Selection
Andrology, EarlyView.ABSTRACT Sperm selection is a critical step in assisted reproductive technology (ART), as sperm quality directly influences embryo quality. In vivo, the female reproductive tract imposes several physical and physiological barriers that favors only the most optimal spermatozoa reaching the fertilization site.
A. Pérez‐Gómez +7 more
wiley +1 more source